iPTMnet Report for P17275 (JUNB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P17275 / JUNB_HUMAN
Protein Name Transcription factor JunB
Gene Name Name: JUNB
Organism Homo sapiens (Human)

PRO ID PR:P17275
DAG View
PRO Name transcription factor JunB (human)
Definition A transcription factor JunB that is encoded in the genome of human.
Short Label hJUNB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P17275 (JUNB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Sumoylation PhosphoSitePlus
K33 Sumoylation PhosphoSitePlus
K36 Acetylation PhosphoSitePlus
K36 Sumoylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
Y47 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
K51 Sumoylation PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
S79 Phosphorylation Q16539 (MAPK14) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 15308641
S84 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
S85 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
S95 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 31373491, 29237092
T100 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
T101 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 31373491, 29237092
T102 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
T102 Phosphorylation Q16539 (MAPK14) , P45983 (MAPK8) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 9889198, 20068231, ...8917518
T104 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
T104 Phosphorylation Q16539 (MAPK14) , P45983 (MAPK8) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 9889198, 8917518, ...20068231
Y109 Phosphorylation PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
S117 O-Glycosylation GlyGen 32119511
S117 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T129 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
T129 Phosphorylation PhosphoSitePlus
T153 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
T153 Phosphorylation IEDB   neXtProt 32897882, 10790372
S158 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
T162 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
Y173 Phosphorylation P00519 (ABL1) PhosphoSitePlus   RLIMS-P 26217035
Y182 Phosphorylation P00519 (ABL1) PhosphoSitePlus   RLIMS-P 26217035
Y188 Phosphorylation P00519 (ABL1) PhosphoSitePlus   RLIMS-P 26217035
S189 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
S189 Phosphorylation neXtProt 10790372
S194 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
S195 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
T204 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
S206 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
S207 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
T210 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
T211 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
T212 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
S214 O-Glycosylation GlyGen 33214551, 34019948, 34725712, ...30059200, 33686291, 29351928, 33950562, 35132862, 31492838, 32119511, 35254053, 29237092
S237 Phosphorylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
K240 Acetylation PhosphoSitePlus
K240 Sumoylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
S251 Phosphorylation P49841 (GSK3B) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 22710716, 18452278, 19651622, ...18669648, 19690332, 20068231
T255 Phosphorylation P49841 (GSK3B) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...22710716, 18452278, 19651622, 18669648, 19690332, 20068231
S259 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18452278, 19651622, 18669648, 19690332
K304 Sumoylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
S311 Phosphorylation HPRD 20068231
S312 Phosphorylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
C336 Methylation IEDB 31844290


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P17275 (JUNB) S79 Q09472 (EP300) unknown eFIP 15308641


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K4 E4 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
Y68 H68 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S85 L85 Biomuta DOID:11054 / urinary bladder cancer [ icgc ]
Y109 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T129 I129 Biomuta DOID:4159 / skin cancer [ cosmic ]
T162 S162 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T211 A211 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T238 A238 Biomuta DOID:10534 / stomach cancer [ cosmic ]