iPTMnet Report for P17181 (IFNAR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P17181 / INAR1_HUMAN
Protein Name Interferon alpha/beta receptor 1 precursor
Gene Name Name: IFNAR1
Synonyms:IFNAR;
Organism Homo sapiens (Human)

PRO ID PR:P17181
DAG View
PRO Name interferon alpha/beta receptor 1 (human)
Definition An interferon-alpha/beta receptor alpha chain that is encoded in the genome of human.
Short Label hIFNAR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P17181 (IFNAR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N58 N-Glycosylation UniProt 19349973
T85 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
N110 N-Glycosylation UniProt 19349973
K125 Ubiquitination PhosphoSitePlus
N172 N-Glycosylation UniProt 21854986
K191 Ubiquitination PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
N313 N-Glycosylation UniProt 19349973
K397 Ubiquitination PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus
Y466 Phosphorylation P29597 (TYK2) phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   UniProt 8605876, 9677371, 7526154, ...11786546, 8700538, 12220192
Y481 Phosphorylation P29597 (TYK2) phospho.ELM   PRO   PhosphoSitePlus   Signor   UniProt 7526154, 8605876
T494 Phosphorylation PhosphoSitePlus
S495 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15659558, 19690332
K501 Ubiquitination UniProt 15337770
K525 Ubiquitination UniProt 15337770
K526 Ubiquitination UniProt 15337770
S532 Phosphorylation Q16539 (MAPK14) PhosphoSitePlus   RLIMS-P 21666722, 21695243
S535 Phosphorylation P48729 (CSNK1A1) , Q9BZL6 (PRKD2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19805514, 21666722, 15337770, ...21695243, 16551269, 18056411, 21865166, 24075985, 19948722, 14532120
Y538 Phosphorylation PhosphoSitePlus
S539 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y466 Phosphorylation P29597 (TYK2) HPRD 9677371
Y481 Phosphorylation P29597 (TYK2) HPRD 95059042
T494 Phosphorylation HPRD 19413330
S495 Phosphorylation HPRD 18578522, 15659558
S535 Phosphorylation HPRD 15337770, 14532120
S539 Phosphorylation HPRD 15337770, 14532120


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047962 (hIFNAR1/SigPep-/Phos:1) pY466,pY481 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y481 H481 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S495 F495 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S539 Y539 Biomuta DOID:1909 / melanoma [ icgc, tcga ]