iPTMnet Report for P17066 (HSPA6)
Protein Information
UniProt AC / UniProt ID | P17066 / HSP76_HUMAN |
Protein Name | Heat shock 70 kDa protein 6 |
Gene Name | Name: HSPA6 Synonyms:HSP70B'; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P17066 |
PRO Name | heat shock 70 kDa protein 6 (human) |
Definition | A heat shock 70 kDa protein 6 that is encoded in the genome of human. |
Short Label | hHSPA6 |
Category | organism-gene |
P17066 (HSPA6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
T40 | Phosphorylation | score1 | PhosphoSitePlus | |||
S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y43 | Phosphorylation | score1 | PhosphoSitePlus | |||
T47 | Phosphorylation | score1 | PhosphoSitePlus | |||
T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
R51 | Methylation | score1 | PhosphoSitePlus | |||
K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
S59 | Phosphorylation | score1 | PhosphoSitePlus | |||
K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
K102 | Ubiquitination | score1 | PhosphoSitePlus | |||
K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
K142 | Methylation | score1 | PhosphoSitePlus | |||
K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y185 | Phosphorylation | score1 | PhosphoSitePlus | |||
T224 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
T228 | Phosphorylation | score1 | PhosphoSitePlus | |||
K259 | Ubiquitination | score1 | PhosphoSitePlus | |||
T267 | Phosphorylation | score1 | PhosphoSitePlus | |||
S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
S298 | Phosphorylation | score1 | PhosphoSitePlus | |||
T300 | Phosphorylation | score1 | PhosphoSitePlus | |||
S309 | Phosphorylation | score1 | PhosphoSitePlus | |||
S314 | Phosphorylation | score1 | PhosphoSitePlus | |||
T315 | Phosphorylation | score1 | PhosphoSitePlus | |||
K321 | Acetylation | score1 | PhosphoSitePlus | |||
K321 | Ubiquitination | score1 | PhosphoSitePlus | |||
K327 | Acetylation | score1 | PhosphoSitePlus | |||
K327 | Ubiquitination | score1 | PhosphoSitePlus | |||
K330 | Methylation | score1 | PhosphoSitePlus | |||
K330 | Ubiquitination | score1 | PhosphoSitePlus | |||
K347 | Ubiquitination | score1 | PhosphoSitePlus | |||
K350 | Acetylation | score1 | PhosphoSitePlus | |||
K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
K359 | Acetylation | score1 | PhosphoSitePlus | |||
K359 | Sumoylation | score1 | PhosphoSitePlus | |||
K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
K363 | Sumoylation | score1 | PhosphoSitePlus | |||
K363 | Ubiquitination | score1 | PhosphoSitePlus | |||
S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y373 | Phosphorylation | score1 | PhosphoSitePlus | |||
K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
S402 | Phosphorylation | score1 | PhosphoSitePlus | |||
T407 | Phosphorylation | score1 | PhosphoSitePlus | |||
K453 | Ubiquitination | score1 | PhosphoSitePlus | |||
R460 | Methylation | score1 | PhosphoSitePlus | |||
R471 | Methylation | score1 | PhosphoSitePlus | |||
R495 | Methylation | score1 | PhosphoSitePlus | |||
K499 | Ubiquitination | score1 | PhosphoSitePlus | |||
K502 | Acetylation | score1 | PhosphoSitePlus | |||
K502 | Ubiquitination | score1 | PhosphoSitePlus | |||
T504 | Phosphorylation | score1 | PhosphoSitePlus | |||
K509 | Acetylation | score1 | PhosphoSitePlus | |||
K509 | Sumoylation | score1 | PhosphoSitePlus | |||
K509 | Ubiquitination | score1 | PhosphoSitePlus | |||
K514 | Ubiquitination | score1 | PhosphoSitePlus | |||
K528 | Ubiquitination | score1 | PhosphoSitePlus | |||
K541 | Ubiquitination | score1 | PhosphoSitePlus | |||
K552 | Ubiquitination | score1 | PhosphoSitePlus | |||
K563 | Methylation | score1 | PhosphoSitePlus | |||
K563 | Ubiquitination | score1 | PhosphoSitePlus | |||
K598 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T40 | A40 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
T47 | A47 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K73 | R73 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S123 | F123 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K128 | N128 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
T267 | K267 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S364 | N364 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R460 | H460 | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
R471 | H471 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
K528 | R528 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
K528 | N528 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
K541 | N541 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] |