iPTMnet Report for P17010 (ZFX)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P17010 / ZFX_HUMAN
Protein Name Zinc finger X-chromosomal protein
Gene Name Name: ZFX
Organism Homo sapiens (Human)

PRO ID PR:P17010
DAG View
PRO Name zinc finger X-chromosomal protein (human)
Definition A zinc finger X-chromosomal protein that is encoded in the genome of human.
Short Label hZFX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P17010 (ZFX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K252 Ubiquitination PhosphoSitePlus
K257 Sumoylation PhosphoSitePlus
T268 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S274 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 15302935
Y425 Phosphorylation PhosphoSitePlus
K468 Sumoylation PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
T571 Phosphorylation PhosphoSitePlus
Y580 Phosphorylation PhosphoSitePlus
K592 Ubiquitination PhosphoSitePlus
T593 O-Glycosylation GlyGen 30379171, 30620550
S600 O-Glycosylation GlyGen 30620550
S600 Phosphorylation PhosphoSitePlus
K649 Sumoylation PhosphoSitePlus
K678 Ubiquitination PhosphoSitePlus
T714 Phosphorylation phospho.ELM 18669648
K715 Ubiquitination PhosphoSitePlus
T771 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T268 Phosphorylation HPRD 18669648
S274 Phosphorylation HPRD 18669648, 15302935
S543 Phosphorylation HPRD 20068231
T657 Phosphorylation HPRD 20068231
T714 Phosphorylation HPRD 18669648
T771 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S543 R543 Biomuta DOID:263 / kidney cancer [ cosmic ]
S543 N543 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T593 M593 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T771 M771 Biomuta DOID:2531 / hematologic cancer [ icgc ]
T771 R771 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]