iPTMnet Report for P16871 (IL7R)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P16871 / IL7RA_HUMAN
Protein Name Interleukin-7 receptor subunit alpha precursor
Gene Name Name: IL7R
Organism Homo sapiens (Human)

PRO ID PR:P16871
DAG View
PRO Name interleukin-7 receptor subunit alpha (human)
Definition An interleukin-7 receptor subunit alpha that is encoded in the genome of human.
Short Label hIL7R
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P16871 (IL7R) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N49 N-Glycosylation GlyGen   UniProt 19141282
N65 N-Glycosylation GlyGen   UniProt 19141282
N151 N-Glycosylation GlyGen   UniProt 19141282, 24190977
Y159 Phosphorylation PhosphoSitePlus
Y169 Phosphorylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
Y449 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus 7719938
Site PTM Type PTM Enzyme Score Source PMID
Y159 Phosphorylation HPRD 17924679
Y169 Phosphorylation HPRD 17924679
Y449 Phosphorylation HPRD 7522165


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048033 (hIL7R/SigPep-/Phos:1) pY449 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N65 H65 Biomuta DOID:263 / kidney cancer [ cosmic ]
N151 K151 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K292 N292 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S297 T297 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K337 N337 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
S365 L365 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S365 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y449 N449 Biomuta DOID:1612 / breast cancer [ cosmic ]