iPTMnet Report for P16860 (NPPB)
Protein Information
| UniProt AC / UniProt ID | P16860 / ANFB_HUMAN |
| Protein Name | Natriuretic peptides B precursor |
| Gene Name | Name: NPPB |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P16860 |
| PRO Name | natriuretic peptides B (human) |
| Definition | A natriuretic peptides B that is encoded in the genome of human. |
| Short Label | hNPPB |
| Category | organism-gene |
DAG ViewP16860 (NPPB) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S41 | O-Glycosylation | score2 | GlyGen UniProt | 32337544 | ||
| T62 | O-Glycosylation | score4 | GlyGen UniProt | 25813380, 16750161 | ||
| S63 | O-Glycosylation | score4 | GlyGen UniProt | 25813380, 16750161 | ||
| S70 | O-Glycosylation | score4 | GlyGen UniProt | 25813380, 16750161 | ||
| T74 | O-Glycosylation | score4 | GlyGen UniProt | 25813380, 16750161 | ||
| S79 | O-Glycosylation | score3 | GlyGen UniProt | 16750161 | ||
| T84 | O-Glycosylation | score3 | GlyGen UniProt | 16750161 | ||
| T84 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T97 | O-Glycosylation | score4 | GlyGen UniProt | 21763278, 16750161 | ||
| S103 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T62 | I62 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| S70 | N70 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S70 | I70 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| T74 | I74 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| S103 | N103 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
