Protein Information

Cytoscape View

UniProt AC / UniProt ID P16591 / FER_HUMAN
Protein Name Tyrosine-protein kinase Fer
Gene Name Name: FER
Organism Homo sapiens (Human)

PRO ID PR:P16591
DAG View
PRO Name tyrosine-protein kinase Fer (human)
Definition A tyrosine-protein kinase Fer that is encoded in the genome of human.
Short Label hFER
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P16591 (FER) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T27 Phosphorylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K173 Acetylation PhosphoSitePlus
Y199 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
K326 Acetylation PhosphoSitePlus
K347 Acetylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
Y402 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18083107, 18691976, 17192257, ...19369195
S408 Phosphorylation PhosphoSitePlus
T410 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
S423 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
S434 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17192257, ...19369195
K453 Ubiquitination PhosphoSitePlus
Y461 Phosphorylation PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
Y492 Phosphorylation PhosphoSitePlus
Y497 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
K579 Ubiquitination PhosphoSitePlus
T586 Phosphorylation PhosphoSitePlus
S587 Phosphorylation PhosphoSitePlus
K591 Ubiquitination PhosphoSitePlus
T592 Phosphorylation PhosphoSitePlus
K594 Ubiquitination PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
Y615 Phosphorylation P16591 (FER) neXtProt   PhosphoSitePlus 19159681
K699 Ubiquitination PhosphoSitePlus
Y714 Phosphorylation P16591 (FER) , P12931 (SRC) neXtProt   phospho.ELM   PhosphoSitePlus 25867068, 10074905, 17192257, ...18083107, 10998246, 19159681
S715 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
K720 Ubiquitination PhosphoSitePlus
Y734 Phosphorylation PhosphoSitePlus
K795 Acetylation PhosphoSitePlus
K795 Ubiquitination PhosphoSitePlus
K812 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y402 Phosphorylation P16591 (FER) HPRD 18691976, 17389395, 17192257
T410 Phosphorylation HPRD 18691976
S411 Phosphorylation HPRD 18691976
S434 Phosphorylation P16591 (FER) HPRD 18691976, 17192257, 20068231
Y714 Phosphorylation P16591 (FER) HPRD 19901323, 10998246, 18691976

P16591 (FER) as PTM Enzyme

Substrate Site Score Source PMID
P10275 (AR) Y225 PhosphoSitePlus   Signor 23906537
P14923 (JUP) Y550 HPRD   PhosphoSitePlus 14517306
P15311 (EZR) Y146 PhosphoSitePlus 25867068
P15311 (EZR) Y354 PhosphoSitePlus 25867068
P15311 (EZR) Y478 PhosphoSitePlus 25867068
P16284 (PECAM1) Y690 neXtProt   Signor 16731527, 12972546
P16284 (PECAM1) Y713 neXtProt   Signor 16731527, 12972546
P16591-1 (FER) Y402 HPRD 18691976, 17389395, 17192257
P16591-1 (FER) S434 HPRD 18691976, 17192257, 20068231
P16591 (FER) Y615 neXtProt   PhosphoSitePlus 19159681
P16591 (FER) Y714 HPRD   neXtProt   PhosphoSitePlus 19901323, 19159681, 10074905, ...18691976, 10998246
P35222 (CTNNB1) Y142 HPRD 12640114
P40763 (STAT3) Y705 neXtProt   PhosphoSitePlus 19147545, 19159681, 10878010
P46459 (NSF) Y83 PhosphoSitePlus 15322554
Q05397 (PTK2) Y861 neXtProt 19339212
Q05397 (PTK2) Y925 neXtProt 19339212
Q14247-3 (CTTN) Y384 HPRD 17016520, 19413330, 17389395, ...18088087, 9748248, 18669648, 18491316, 18707149, 17287340, 20068231, 16497976
Q14247-1 (CTTN) Y421 HPRD 17016520, 19413330, 17389395, ...17287340, 10921917, 9748248, 18669648, 18491316, 18707149, 18088087, 20068231, 16497976

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O15117 (FYB1) Y595 P16591 (FER) unknown eFIP 22074159
Phosphorylation P21860 (ERBB3) Y1289 P16591 (FER) unknown eFIP 16273093
Phosphorylation Q8IZP0 (ABI1) Y421 P16591 (FER) unknown eFIP 20598684