iPTMnet Report for P16581 (SELE)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P16581 / LYAM2_HUMAN
Protein Name E-selectin precursor
Gene Name Name: SELE
Synonyms:ELAM1;
Organism Homo sapiens (Human)

PRO ID PR:P16581
DAG View
PRO Name E-selectin (human)
Definition An E-selectin that is encoded in the genome of human.
Short Label hSELE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P16581 (SELE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y24 Phosphorylation PhosphoSitePlus
N25 N-Glycosylation GlyGen   UniProt 26117840
K76 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
N145 N-Glycosylation GlyGen   UniProt 26117840
N160 N-Glycosylation GlyGen   UniProt 26117840
N179 N-Glycosylation GlyGen   UniProt 26117840
N199 N-Glycosylation GlyGen   UniProt 26117840
N203 N-Glycosylation GlyGen   UniProt 26117840
N265 N-Glycosylation GlyGen   UniProt 26117840
S318 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
Y390 Phosphorylation PhosphoSitePlus
T452 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
Y603 Phosphorylation HPRD   IntAct 11602579


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N25 S25 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
N25 H25 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K76 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
K117 M117 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S383 G383 Biomuta DOID:9256 / colorectal cancer [ cosmic ]