iPTMnet Report for P16519 (PCSK2)
Protein Information
| UniProt AC / UniProt ID | P16519 / NEC2_HUMAN |
| Protein Name | Neuroendocrine convertase 2 precursor |
| Gene Name | Name: PCSK2 Synonyms:NEC2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P16519 |
| PRO Name | neuroendocrine convertase 2 (human) |
| Definition | A neuroendocrine convertase 2 that is encoded in the genome of human. |
| Short Label | hPCSK2 |
| Category | organism-gene |
DAG ViewP16519 (PCSK2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T210 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N375 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
| N524 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| Y607 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N375 | S375 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| N524 | S524 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y607 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] |
