iPTMnet Report for P16519 (PCSK2)
Protein Information
UniProt AC / UniProt ID | P16519 / NEC2_HUMAN |
Protein Name | Neuroendocrine convertase 2 precursor |
Gene Name | Name: PCSK2 Synonyms:NEC2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P16519 |
PRO Name | neuroendocrine convertase 2 (human) |
Definition | A neuroendocrine convertase 2 that is encoded in the genome of human. |
Short Label | hPCSK2 |
Category | organism-gene |
P16519 (PCSK2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
T210 | Phosphorylation | score1 | PhosphoSitePlus | |||
N375 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
N524 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
Y607 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N375 | S375 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
N524 | S524 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y607 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] |