iPTMnet Report for P16499 (PDE6A)
Protein Information
| UniProt AC / UniProt ID | P16499 / PDE6A_HUMAN |
| Protein Name | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha precursor |
| Gene Name | Name: PDE6A Synonyms:PDEA; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P16499 |
| PRO Name | rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (human) |
| Definition | A rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha that is encoded in the genome of human. |
| Short Label | hPDE6A |
| Category | organism-gene |
DAG ViewP16499 (PDE6A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K84 | Methylation | score1 | PhosphoSitePlus | |||
| S180 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y264 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y275 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K467 | Acetylation | score1 | PhosphoSitePlus | |||
| K677 | Acetylation | score1 | PhosphoSitePlus | |||
| T717 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K677 | Q677 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
