iPTMnet Report for P16473 (TSHR)
Protein Information
| UniProt AC / UniProt ID | P16473 / TSHR_HUMAN |
| Protein Name | Thyrotropin receptor precursor |
| Gene Name | Name: TSHR Synonyms:LGR3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P16473 |
| PRO Name | thyrotropin receptor (human) |
| Definition | A thyrotropin receptor that is encoded in the genome of human. |
| Short Label | hTSHR |
| Category | organism-gene |
DAG ViewP16473 (TSHR) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K42 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N77 | N-Glycosylation | score4 | GlyGen UniProt | 11502179, 17542669, 2017190 | ||
| N99 | N-Glycosylation | score3 | GlyGen UniProt | 17542669 | ||
| N113 | N-Glycosylation | score4 | GlyGen UniProt | 11502179, 17542669, 2017190 | ||
| N177 | N-Glycosylation | score3 | GlyGen UniProt | 17542669 | ||
| N198 | N-Glycosylation | score4 | GlyGen UniProt | 11502179, 17542669 | ||
| Y225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S268 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S298 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N302 | N-Glycosylation | score3 | GlyGen UniProt | 11502179 | ||
| S308 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S425 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y706 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y739 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S745 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T748 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S226 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S229 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S226 | R226 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
