iPTMnet Report for P16452 (EPB42)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P16452 / EPB42_HUMAN
Protein Name Protein 4.2
Gene Name Name: EPB42
Synonyms:E42P;
Organism Homo sapiens (Human)

PRO ID PR:P16452
DAG View
PRO Name protein 4.2 (human)
Definition A protein 4.2 that is encoded in the genome of human.
Short Label hEPB42
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P16452 (EPB42) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 1544941
S82 O-Glycosylation GlyGen   PhosphoSitePlus 18984734, 28411811
S248 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 8499466
T291 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
T375 Phosphorylation PhosphoSitePlus
T403 Phosphorylation PhosphoSitePlus
T407 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
Y435 Phosphorylation PhosphoSitePlus
T560 Phosphorylation PhosphoSitePlus
T565 Phosphorylation PhosphoSitePlus
K593 Methylation PhosphoSitePlus
S690 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S82 P82 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T291 A291 Biomuta DOID:1324 / lung cancer [ cosmic ]
T291 M291 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S294 L294 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T375 M375 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
T411 K411 Biomuta DOID:1324 / lung cancer [ cosmic ]
T560 A560 Biomuta DOID:363 / uterine cancer [ icgc ]
T560 I560 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T565 N565 Biomuta DOID:3571 / liver cancer [ cosmic ]