iPTMnet Report for P16383 (GCFC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P16383 / GCFC2_HUMAN
Protein Name Intron Large complex component GCFC2
Gene Name Name: GCFC2
Synonyms:C2orf3,GCF,TCF9;
Organism Homo sapiens (Human)

PRO ID PR:P16383
DAG View
PRO Name intron Large complex component GCFC2 (human)
Definition An intron Large complex component GCFC2 that is encoded in the genome of human.
Short Label hGCFC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P16383 (GCFC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 24275569, ...19690332
S17 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 24275569, ...19690332
S19 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 19690332
S25 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus   UniProt 23186163
R51 Methylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
K79 Methylation PhosphoSitePlus
S96 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
T97 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
S106 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
S174 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S180 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
T192 Phosphorylation PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
T213 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S214 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S217 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S246 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
T259 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
K411 Acetylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
T428 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S429 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 15302935
S430 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 15302935
K452 Ubiquitination PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
T557 Phosphorylation PhosphoSitePlus
Y627 Phosphorylation PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
Y681 Phosphorylation PhosphoSitePlus
K775 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S17 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S19 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S40 Phosphorylation HPRD 19413330
S96 Phosphorylation HPRD 19651622, 18767875, 17081983, ...20068231
T97 Phosphorylation HPRD 19651622, 18767875, 17081983, ...20068231
S119 Phosphorylation HPRD 19413330
S174 Phosphorylation HPRD 19651622, 18669648
S180 Phosphorylation HPRD 19651622, 18669648, 17081983
T213 Phosphorylation HPRD 18669648
S214 Phosphorylation HPRD 18669648, 18452278
S217 Phosphorylation HPRD 18669648, 18452278
T259 Phosphorylation HPRD 18452278
S262 Phosphorylation HPRD 18452278
Y376 Phosphorylation HPRD 17322306
T428 Phosphorylation HPRD 18669648, 20068231
S429 Phosphorylation HPRD 18669648, 15302935, 20068231
S430 Phosphorylation HPRD 18669648, 15302935, 20068231
S436 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S207 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 F16 Biomuta DOID:4159 / skin cancer [ cosmic ]
R51 S51 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S73 C73 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T97 A97 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S106 F106 Biomuta [ cosmic ]
S207 R207 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S262 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S262 L262 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
S419 F419 Biomuta DOID:4159 / skin cancer [ cosmic ]
K513 N513 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y627 S627 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y627 C627 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K629 N629 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S637 T637 Biomuta DOID:10534 / stomach cancer [ cosmic ]