Protein Information

Cytoscape View


UniProt AC / UniProt ID P16070 / CD44_HUMAN
Protein Name CD44 antigen precursor
Gene Name Name: CD44
Synonyms:LHR,MDU2,MDU3,MIC4;
Organism Homo sapiens (Human)

PRO ID PR:P16070
DAG View
PRO Name CD44 antigen (human)
Definition A CD44 molecule that is encoded in the genome of human.
Short Label hCD44
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P16070 (CD44) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N25 N-Glycosylation GlyGen 29741879
S45 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K54 Ubiquitination PhosphoSitePlus
N57 N-Glycosylation GlyGen   UniProt 16335952, 30237853, 19159218, ...24190977, 23090970, 29391424, 29741879
S58 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T62 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
N100 N-Glycosylation GlyGen 22722744
N110 N-Glycosylation GlyGen   UniProt 19159218
K158 Ubiquitination PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
T174 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S179 Phosphorylation PhosphoSitePlus
S180 O-Glycosylation GlyGen   UniProt 25326458, 36213313, 32337544
S182 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
T197 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S199 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
T200 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
T222 Phosphorylation PhosphoSitePlus
T271 O-Glycosylation GlyGen 30459171
N282 N-Glycosylation GlyGen 24190977
S291 Phosphorylation phospho.ELM   RLIMS-P 12032545, 32697798
T311 Phosphorylation PhosphoSitePlus
T318 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T325 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S330 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S332 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
N350 N-Glycosylation GlyGen 24190977
T398 O-Glycosylation GlyGen 30459171
Y412 O-Glycosylation GlyGen 23584533, 25813380
Y412 Phosphorylation PhosphoSitePlus
T415 O-Glycosylation GlyGen 23584533
S420 O-Glycosylation GlyGen 25813380
S420 Phosphorylation PhosphoSitePlus
S422 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T423 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T424 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T426 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S430 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T433 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S434 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S458 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S478 O-Glycosylation GlyGen 23584533
T480 O-Glycosylation GlyGen 23584533
T484 O-Glycosylation GlyGen 23584533, 30459171
T489 O-Glycosylation GlyGen 23584533, 30459171
S514 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T515 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T528 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T529 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T541 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
N548 N-Glycosylation GlyGen 24190977
S550 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S553 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T554 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
T555 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
Y560 O-Glycosylation GlyGen 23584533, 23399548, 25813380
T561 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S562 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
Y564 O-Glycosylation GlyGen 25813380
T567 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S570 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T572 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T572 Phosphorylation PhosphoSitePlus
T577 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S578 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T581 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S583 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T587 Phosphorylation PhosphoSitePlus
N595 N-Glycosylation GlyGen 24190977
N597 N-Glycosylation GlyGen 24190977
N599 N-Glycosylation GlyGen 24190977
S627 O-Glycosylation GlyGen 30459171
T637 O-Glycosylation GlyGen 25813380, 22171320
T638 O-Glycosylation GlyGen 25813380, 22171320
S672 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 12032545
S672 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 12032545
K681 Acetylation PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
S686 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
K695 Ubiquitination PhosphoSitePlus
S697 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   Signor 18669648, 16785995, 17081983
S697 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   Signor 16785995
S704 Phosphorylation PhosphoSitePlus
K705 Ubiquitination PhosphoSitePlus
S706 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 18691976, 21406692, 23186163, ...17081983, 12032545, 9580567, 19367720, 18669648, 20068231, 11463356
S706 Phosphorylation Q9UQM7 (CAMK2A) PhosphoSitePlus   Signor 9580567, 11463356
K715 Ubiquitination PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus
T720 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
T726 Phosphorylation PhosphoSitePlus
K739 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation HPRD 18669648
S58 Phosphorylation HPRD 18669648
T62 Phosphorylation HPRD 18669648
T587 Phosphorylation HPRD 18452278
S672 Phosphorylation HPRD 12032545
S686 Phosphorylation HPRD 18578522, 18669648, 20068231
S697 Phosphorylation HPRD 20068231, 18077418, 18669648, ...18578522
S704 Phosphorylation HPRD 18578522, 20068231
S706 Phosphorylation HPRD 18691976, 18578522, 12032545, ...9580567, 18077418, 18707149, 18452278, 19651622, 18669648, 18767875, 20068231, 11463356
S717 Phosphorylation HPRD 20068231, 18452278
S718 Phosphorylation HPRD 18578522, 18452278
T720 Phosphorylation HPRD 18578522, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation HPRD 18669648
S58 Phosphorylation HPRD 18669648
T62 Phosphorylation HPRD 18669648
T338 Phosphorylation HPRD 18452278
S423 Phosphorylation HPRD 12032545
S437 Phosphorylation HPRD 18578522, 18669648, 20068231
S448 Phosphorylation HPRD 20068231, 18077418, 18669648, ...18578522
S455 Phosphorylation HPRD 18578522, 20068231
S457 Phosphorylation HPRD 18691976, 18578522, 12032545, ...9580567, 18077418, 18707149, 18452278, 19651622, 18669648, 18767875, 20068231, 11463356
S468 Phosphorylation HPRD 20068231, 18452278
S469 Phosphorylation HPRD 18578522, 18452278
T471 Phosphorylation HPRD 18578522, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation HPRD 18669648
S58 Phosphorylation HPRD 18669648
T62 Phosphorylation HPRD 18669648
S291 Phosphorylation HPRD   PhosphoSitePlus 12032545
S305 Phosphorylation HPRD 18578522, 18669648, 20068231
S316 Phosphorylation HPRD 20068231, 18077418, 18669648, ...18578522
S323 Phosphorylation HPRD 18578522, 20068231
S325 Phosphorylation HPRD   PhosphoSitePlus 18691976, 18578522, 12032545, ...9580567, 18077418, 18707149, 18452278, 19651622, 18669648, 18767875, 20068231, 11463356
S336 Phosphorylation HPRD 20068231, 18452278
S337 Phosphorylation HPRD 18578522, 18452278
T339 Phosphorylation HPRD 18578522, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation HPRD 18669648
S58 Phosphorylation HPRD 18669648
T62 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation HPRD 18669648
S58 Phosphorylation HPRD 18669648
T62 Phosphorylation HPRD 18669648
T544 Phosphorylation HPRD 18452278
S629 Phosphorylation HPRD 12032545
S643 Phosphorylation HPRD 18578522, 18669648, 20068231
S654 Phosphorylation HPRD 20068231, 18077418, 18669648, ...18578522
S661 Phosphorylation HPRD 18578522, 20068231
S663 Phosphorylation HPRD 18691976, 18578522, 12032545, ...9580567, 18077418, 18707149, 18452278, 19651622, 18669648, 18767875, 20068231, 11463356
S674 Phosphorylation HPRD 20068231, 18452278
S675 Phosphorylation HPRD 18578522, 18452278
T677 Phosphorylation HPRD 18578522, 18669648, 20068231


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P35240 (NF2) S518 P16070 (CD44) unknown eFIP 19141242