Protein Information

Cytoscape View


UniProt AC / UniProt ID P16035 / TIMP2_HUMAN
Protein Name Metalloproteinase inhibitor 2 precursor
Gene Name Name: TIMP2
Organism Homo sapiens (Human)

PRO ID PR:P16035
DAG View
PRO Name metalloproteinase inhibitor 2 (human)
Definition A metalloproteinase inhibitor 2 that is encoded in the genome of human.
Short Label hTIMP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P16035 (TIMP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K53 Ubiquitination PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y90 C90 Biomuta DOID:1115 / sarcoma [ tcga ]