Protein Information

Cytoscape View


UniProt AC / UniProt ID P16035 / TIMP2_HUMAN
Protein Name Metalloproteinase inhibitor 2 precursor
Gene Name Name: TIMP2
Organism Homo sapiens (Human)

PRO ID PR:P16035
DAG View
PRO Name metalloproteinase inhibitor 2 (human)
Definition A metalloproteinase inhibitor 2 that is encoded in the genome of human.
Short Label hTIMP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P16035 (TIMP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K53 Ubiquitination PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus   RLIMS-P 30227959
K67 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus   RLIMS-P 30227959
Y165 Phosphorylation PhosphoSitePlus   RLIMS-P 30227959


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y90 C90 Biomuta DOID:1115 / sarcoma [ tcga ]