iPTMnet Report for P16035 (TIMP2)
Protein Information
| UniProt AC / UniProt ID | P16035 / TIMP2_HUMAN |
| Protein Name | Metalloproteinase inhibitor 2 precursor |
| Gene Name | Name: TIMP2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P16035 |
| PRO Name | metalloproteinase inhibitor 2 (human) |
| Definition | A metalloproteinase inhibitor 2 that is encoded in the genome of human. |
| Short Label | hTIMP2 |
| Category | organism-gene |
DAG ViewP16035 (TIMP2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y62 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 30227959 | ||
| K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K74 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y90 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 30227959 | ||
| Y165 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 30227959 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S57 | I57 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y90 | C90 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] |
