iPTMnet Report for P15884 (TCF4)
Protein Information
| UniProt AC / UniProt ID | P15884 / ITF2_HUMAN |
| Protein Name | Transcription factor 4 |
| Gene Name | Name: TCF4 Synonyms:BHLHB19,ITF2,SEF2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P15884 |
| PRO Name | transcription factor 4 (human) |
| Definition | A transcription factor 4 that is encoded in the genome of human. |
| Short Label | hTCF4 |
| Category | organism-gene |
DAG ViewP15884 (TCF4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S54 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11711551 | ||
| S55 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11711551 | ||
| S56 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11711551 | ||
| S66 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S87 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S92 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| R106 | Methylation | score1 | PhosphoSitePlus | |||
| Y149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T297 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N301 | N-Glycosylation | score1 | GlyGen | 29671580 | ||
| S318 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T320 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T337 | Phosphorylation | score1 | IEDB | 32357974 | ||
| S340 | Phosphorylation | score1 | IEDB | 32357974 | ||
| S372 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18220336 | ||
| Y375 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S484 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S515 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
| T554 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K585 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K629 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N301 | N-Glycosylation | score1 | PRO | 29671580 | ||
| S481 | Phosphorylation | score0 | HPRD | 19651622 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T487 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S383 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S389 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T398 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S68 | F68 | Biomuta | [ cosmic ] | |
| S92 | P92 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S92 | T92 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S318 | F318 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T320 | A320 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S340 | R340 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| S383 | L383 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S484 | F484 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S515 | P515 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S515 | F515 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
