Protein Information

Cytoscape View


UniProt AC / UniProt ID P15880 / RS2_HUMAN
Protein Name 40S ribosomal protein S2
Gene Name Name: RPS2
Synonyms:RPS4;
Organism Homo sapiens (Human)

PRO ID PR:P15880
DAG View
PRO Name 40S ribosomal protein S2 (human)
Definition A 40S ribosomal protein S2 that is encoded in the genome of human.
Short Label hRPS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P15880 (RPS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
R22 Methylation PhosphoSitePlus
R26 Methylation PhosphoSitePlus
R34 Methylation PhosphoSitePlus
R36 Methylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus   UniProt 28132843
K65 Ubiquitination PhosphoSitePlus
K76 Sumoylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
K103 Sumoylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K108 Sumoylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
Y133 Phosphorylation HPRD   PhosphoSitePlus 20068231
K145 Ubiquitination PhosphoSitePlus
R167 Methylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K176 Acetylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
C182 S-Nitrosylation dbSNO 26338901
K183 Ubiquitination PhosphoSitePlus
C188 S-Nitrosylation dbSNO 26338901
S190 Phosphorylation PhosphoSitePlus
T202 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
K211 Acetylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
T224 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
R227 Methylation PhosphoSitePlus
C229 S-Nitrosylation dbSNO 19483679
K238 Methylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus
Y248 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus   UniProt 23186163
K257 Acetylation PhosphoSitePlus
K257 Methylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
T262 Phosphorylation HPRD   PhosphoSitePlus 20068231
K263 Acetylation PhosphoSitePlus   UniProt 19608861
K263 Sumoylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
S264 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 19651622, ...18669648, 20068231
Y266 Phosphorylation PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus   UniProt 23186163
K275 Acetylation PhosphoSitePlus   UniProt 19608861
K275 Sumoylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus   UniProt 28132843
T276 Phosphorylation PhosphoSitePlus
T278 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 17287340, 20068231
R279 Methylation PhosphoSitePlus
S281 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 17081983, 20068231
T285 O-Glycosylation GlyGen 18369606, 30059200, 21740066, ...32119511, 28510447, 22121020, 29237092
T285 Phosphorylation PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus
T293 O-Glycosylation GlyGen 18369606, 30059200, 21740066, ...32119511, 28510447, 22121020, 29237092
T293 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16964243, 20068231, 19007248


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R22 L22 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K54 N54 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
Y223 C223 Biomuta DOID:1612 / breast cancer [ cosmic ]
S225 L225 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
Y248 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
K275 N275 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]