iPTMnet Report for P15559 (NQO1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P15559 / NQO1_HUMAN
Protein Name NAD(P)H dehydrogenase [quinone] 1
Gene Name Name: NQO1
Synonyms:DIA4,NMOR1;
Organism Homo sapiens (Human)

PRO ID PR:P15559
DAG View
PRO Name NAD(P)H dehydrogenase [quinone] 1 (human)
Definition An NAD(P)H dehydrogenase [quinone] 1 that is encoded in the genome of human.
Short Label hNQO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P15559 (NQO1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
Y20 Phosphorylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
K31 Acetylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
Y43 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K59 Acetylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K61 Acetylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
K77 Acetylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus   UniProt 23186163
K90 Acetylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
T128 Phosphorylation PhosphoSitePlus
Y129 Phosphorylation PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K209 Acetylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K210 Acetylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K251 Acetylation PhosphoSitePlus
K251 Sumoylation PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
K262 Acetylation PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K271 Sumoylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036290 (hNQO1/iso:1/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K23 N23 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y43 D43 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y68 H68 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S82 I82 Biomuta [ cosmic ]
K135 Q135 Biomuta DOID:2021 / placenta cancer [ cosmic ]