iPTMnet Report for P15498 (VAV1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P15498 / VAV_HUMAN
Protein Name Proto-oncogene vav
Gene Name Name: VAV1
Synonyms:VAV;
Organism Homo sapiens (Human)

PRO ID PR:P15498
DAG View
PRO Name proto-oncogene vav (human)
Definition A proto-oncogene vav that is encoded in the genome of human.
Short Label hVAV1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P15498 (VAV1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K73 Ubiquitination PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
Y142 Phosphorylation P06239 (LCK) phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 16285729
Y160 Phosphorylation P06239 (LCK) IntAct   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 24596147, 15699036, 16285729, ...17050525
Y174 Phosphorylation P06239 (LCK) , P43405 (SYK) IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 23758320, 898671, 10636924, ...18301737, 28507287, 10669745, 18779373, 26659126, 29058761, 21606197, 32698503, 19412549, 20028078, 28832024, 23620790, 10544657, 16285729, 8986718, 27926862, 17050525
S180 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
Y192 Phosphorylation PhosphoSitePlus
K194 Acetylation PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
K222 Acetylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
K252 Acetylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
Y267 Phosphorylation P00519 (ABL1) PhosphoSitePlus   RLIMS-P 23325923, 29058761
Y280 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
K345 Acetylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K487 Acetylation PhosphoSitePlus
Y541 Phosphorylation PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
T574 Phosphorylation IEDB   PhosphoSitePlus 35494241
K576 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
Y603 Phosphorylation PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus
C652 Methylation IEDB 31844290
S683 Phosphorylation PhosphoSitePlus
K700 Ubiquitination PhosphoSitePlus
K716 Acetylation PhosphoSitePlus
K716 Ubiquitination PhosphoSitePlus
K732 Acetylation PhosphoSitePlus
K732 Ubiquitination PhosphoSitePlus
K733 Acetylation PhosphoSitePlus
Y745 Phosphorylation PhosphoSitePlus   RLIMS-P 20028078
K751 Ubiquitination PhosphoSitePlus
K755 Ubiquitination PhosphoSitePlus
K766 Ubiquitination PhosphoSitePlus
K770 Ubiquitination PhosphoSitePlus
S774 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
K782 Ubiquitination PhosphoSitePlus
Y783 Phosphorylation PhosphoSitePlus
T786 Phosphorylation PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
Y791 Phosphorylation PhosphoSitePlus
K804 Ubiquitination PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
K815 Ubiquitination PhosphoSitePlus
Y826 Phosphorylation PhosphoSitePlus   UniProt 15592455
Y836 Phosphorylation PhosphoSitePlus
Y841 Phosphorylation PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus
Y844 Phosphorylation phospho.ELM   PhosphoSitePlus 16497976
Site PTM Type PTM Enzyme Score Source PMID
Y142 Phosphorylation P06239 (LCK) HPRD 10669745
Y160 Phosphorylation P06239 (LCK) HPRD 10669745
Y174 Phosphorylation P06239 (LCK) HPRD 10669745
Y826 Phosphorylation HPRD 15592455
Y836 Phosphorylation HPRD 16497976
Y841 Phosphorylation HPRD 16497976
Y844 Phosphorylation HPRD 16497976
Site PTM Type PTM Enzyme Score Source PMID
K190 Ubiquitination PhosphoSitePlus
S748 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049642 (hVAV1/Phos:2) pY142,pY160,pY174 PRO
PR:000049643 (hVAV1/Phos:3) pY174 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P22681 (CBL) Y700 P15498 (VAV1) unknown eFIP 12881521
Phosphorylation Q13094 (LCP2) Y113 P15498 (VAV1) unknown eFIP 22786724