iPTMnet Report for P15408 (FOSL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P15408 / FOSL2_HUMAN
Protein Name Fos-related antigen 2
Gene Name Name: FOSL2
Synonyms:FRA2;
Organism Homo sapiens (Human)

PRO ID PR:P15408
DAG View
PRO Name Fos-related antigen 2 (human)
Definition A Fos-related antigen 2 that is encoded in the genome of human.
Short Label hFOSL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P15408 (FOSL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
Y2 Phosphorylation PhosphoSitePlus
Y5 Phosphorylation PhosphoSitePlus
S16 Phosphorylation phospho.ELM 18669648
S17 Phosphorylation PhosphoSitePlus
S19 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K35 Ubiquitination PhosphoSitePlus
T55 O-Glycosylation GlyGen 29485866, 33214551, 34725712, ...34019948, 29351928
T56 O-Glycosylation GlyGen 29485866, 33214551, 34725712, ...34019948, 29351928
S57 O-Glycosylation GlyGen 29485866, 33214551, 34725712, ...34019948, 29351928
T67 O-Glycosylation GlyGen 29485866, 33214551, 34725712, ...34019948, 29351928
Y76 Phosphorylation PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
S83 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K104 Acetylation PhosphoSitePlus
K104 Methylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23186163, 23807221, 20068231
K135 Acetylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S200 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 23186163, 17081983, ...18220336, 15302935, 18669648, 23807221, 20068231
S211 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S215 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K222 Acetylation PhosphoSitePlus
K222 Sumoylation PhosphoSitePlus
S230 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 15302935, 18669648, ...23807221, 20068231
S232 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S233 Phosphorylation PhosphoSitePlus
S235 Phosphorylation phospho.ELM 18669648
K240 Acetylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
T263 O-Glycosylation GlyGen 29485866, 33214551, 34725712, ...34019948, 29351928
S269 O-Glycosylation GlyGen 29485866, 33214551, 34725712, ...34019948, 29351928
T270 O-Glycosylation GlyGen 29485866, 33214551, 34725712, ...34019948, 29351928
S307 Phosphorylation PhosphoSitePlus
S308 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S309 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S310 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S317 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 25547114, 23807221, 20068231
T322 Phosphorylation PhosphoSitePlus   RLIMS-P 25547114, 23807221
Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation HPRD 18669648
S17 Phosphorylation HPRD 18452278
S19 Phosphorylation HPRD 18669648, 20068231, 18452278
S79 Phosphorylation HPRD 17081983
S83 Phosphorylation HPRD 18669648, 17081983
S120 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S200 Phosphorylation HPRD 17322306, 18212344, 20058876, ...18452278, 19651622, 18669648, 19415658, 20068231
S211 Phosphorylation HPRD 18669648, 20068231
S215 Phosphorylation HPRD 18669648
S230 Phosphorylation HPRD 15302935, 18669648, 20058876, ...20068231, 18452278
S232 Phosphorylation HPRD 18669648, 18452278
S233 Phosphorylation HPRD 20068231, 18452278
S235 Phosphorylation HPRD 18669648
S307 Phosphorylation HPRD 18452278
S308 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S309 Phosphorylation HPRD 18669648, 20068231, 18452278
S310 Phosphorylation HPRD 18669648
S320 Phosphorylation HPRD 17081983, 20068231, 18452278
T322 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S194 N194 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S200 L200 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S211 N211 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S211 G211 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S215 A215 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S215 L215 Biomuta DOID:1324 / lung cancer [ cosmic ]
K222 N222 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S232 L232 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S233 P233 Biomuta DOID:4159 / skin cancer [ cosmic ]
S235 L235 Biomuta DOID:4159 / skin cancer [ cosmic ]
K240 R240 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S310 I310 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S317 F317 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]