iPTMnet Report for P15407 (FOSL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P15407 / FOSL1_HUMAN
Protein Name Fos-related antigen 1
Gene Name Name: FOSL1
Synonyms:FRA1;
Organism Homo sapiens (Human)

PRO ID PR:P15407
DAG View
PRO Name Fos-related antigen 1 (human)
Definition A Fos-related antigen 1 that is encoded in the genome of human.
Short Label hFOSL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P15407 (FOSL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R66 Methylation PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus
S74 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
R79 Methylation PhosphoSitePlus
R84 Methylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
K116 Acetylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
T183 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
T217 Phosphorylation PhosphoSitePlus
T223 Phosphorylation Q04759 (PRKCQ) PhosphoSitePlus   RLIMS-P 22286759
T227 Phosphorylation PhosphoSitePlus
T230 Phosphorylation Q04759 (PRKCQ) PhosphoSitePlus   RLIMS-P 22286759
T240 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus   RLIMS-P 29382358
S253 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
S265 Phosphorylation Q04759 (PRKCQ) PhosphoSitePlus   RLIMS-P   UniProt 29382358, 20068231, 22286759
T267 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S251 Phosphorylation HPRD 20068231
S259 Phosphorylation HPRD 20068231
S260 Phosphorylation HPRD 20068231
S265 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T69 S69 Biomuta DOID:1324 / lung cancer [ tcga ]
R79 L79 Biomuta DOID:1324 / lung cancer [ tcga ]
R79 W79 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R84 L84 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
R84 Q84 Biomuta DOID:1319 / brain cancer [ icgc ]
T217 I217 Biomuta DOID:0060119 / pharynx cancer [ cosmic ]
T267 A267 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]