Protein Information

Cytoscape View


UniProt AC / UniProt ID P15391 / CD19_HUMAN
Protein Name B-lymphocyte antigen CD19 precursor
Gene Name Name: CD19
Organism Homo sapiens (Human)

PRO ID PR:P15391
DAG View
PRO Name B-lymphocyte antigen CD19 (human)
Definition A CD19 molecule that is encoded in the genome of human.
Short Label hCD19
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P15391 (CD19) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N86 N-Glycosylation GlyGen   UniProt 29490423
N125 N-Glycosylation GlyGen   UniProt 29490423, 24190977
N138 N-Glycosylation GlyGen 24190977
T337 Phosphorylation PhosphoSitePlus
Y348 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus   UniProt 10706702
T356 Phosphorylation PhosphoSitePlus
Y378 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus   UniProt 10706702
Y409 Phosphorylation P07948 (LYN) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   UniProt 10706702, 10933394
Y439 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus   UniProt 10706702
T475 Phosphorylation PhosphoSitePlus
S497 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S499 Phosphorylation PhosphoSitePlus
Y500 Phosphorylation P07948 (LYN) IntAct   phospho.ELM   PRO   PhosphoSitePlus   Signor   UniProt 7684160, 9190913, 10933394
Y508 Phosphorylation P00519 (ABL1) neXtProt   PhosphoSitePlus 11120811
S515 Phosphorylation PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus
Y531 Phosphorylation P07948 (LYN) IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 7684160, 30569825, 9190913, ...10933394
Site PTM Type PTM Enzyme Score Source PMID
Y348 Phosphorylation P28482 (MAPK1) HPRD 10706702, 16497976
Y378 Phosphorylation P28482 (MAPK1) HPRD 10706702
Y409 Phosphorylation P07948 (LYN) , P28482 (MAPK1) HPRD 10706702, 10933394
Y439 Phosphorylation P28482 (MAPK1) HPRD 10706702
S497 Phosphorylation HPRD 17525332
Y500 Phosphorylation P07948 (LYN) , Q06187 (BTK) HPRD 10933394, 10201980
Y508 Phosphorylation P00519 (ABL1) HPRD 11120811
Y531 Phosphorylation P07948 (LYN) , Q06187 (BTK) HPRD 10933394, 16497976


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046613 (hCD19/SigPep-/Phos:1) pY348,pY378,pY409,pY439,pY500,pY531 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P15391 (CD19) Y531 P27986 (PIK3R1) unknown eFIP 7684160


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N86 D86 Biomuta DOID:363 / uterine cancer [ tcga ]
S497 Y497 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S499 T499 Biomuta DOID:363 / uterine cancer [ tcga ]
Y500 C500 Biomuta DOID:1324 / lung cancer [ cosmic ]