iPTMnet Report for P15260 (IFNGR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P15260 / INGR1_HUMAN
Protein Name Interferon gamma receptor 1 precursor
Gene Name Name: IFNGR1
Organism Homo sapiens (Human)

PRO ID PR:P15260
DAG View
PRO Name interferon gamma receptor 1 (human)
Definition An interferon gamma receptor alpha chain that is encoded in the genome of human.
Short Label hIFNGR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P15260 (IFNGR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N34 N-Glycosylation GlyGen 8142896
N79 N-Glycosylation GlyGen 8142896
N86 N-Glycosylation GlyGen 8142896
K115 Ubiquitination PhosphoSitePlus
C122 Methylation IEDB 31844290
N179 N-Glycosylation GlyGen 23090970, 29741879, 8142896, ...24190977
S262 Phosphorylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
T295 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
T309 Phosphorylation PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
Y311 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
S327 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
Y397 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
Y457 Phosphorylation P23458 (JAK1) IntAct   phospho.ELM   PRO   PhosphoSitePlus   Signor   UniProt 15780933, 8662591, 8156998, ...7615558
K459 Ubiquitination PhosphoSitePlus
Y479 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N34 N-Glycosylation PRO 8142896
N79 N-Glycosylation PRO 8142896
N86 N-Glycosylation PRO 8142896
N179 N-Glycosylation PRO 8142896
Y457 Phosphorylation HPRD 8156998


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047965 (hIFNGR1/SigPep-/Phos:1) pY457 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S306 * Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S306 P306 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S306 L306 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T309 M309 Biomuta DOID:363 / uterine cancer [ icgc ]
S315 F315 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S391 N391 Biomuta DOID:4159 / skin cancer [ cosmic ]
S396 L396 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S403 C403 Biomuta DOID:2998 / testicular cancer [ cosmic ]