iPTMnet Report for P15170 (GSPT1)
Protein Information
UniProt AC / UniProt ID | P15170 / ERF3A_HUMAN |
Protein Name | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A |
Gene Name | Name: GSPT1 Synonyms:ERF3A; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P15170 |
PRO Name | eukaryotic peptide chain release factor GTP-binding subunit ERF3A (human) |
Definition | A eukaryotic peptide chain release factor GTP-binding subunit ERF3A that is encoded in the genome of human. |
Short Label | hGSPT1 |
Category | organism-gene |
P15170 (GSPT1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
S46 | Phosphorylation | score1 | PhosphoSitePlus | |||
S62 | Phosphorylation | score1 | PhosphoSitePlus | |||
K71 | Ubiquitination | score1 | PhosphoSitePlus | |||
K108 | Acetylation | score1 | PhosphoSitePlus | |||
K108 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y109 | Phosphorylation | score1 | PhosphoSitePlus | |||
T120 | Phosphorylation | score1 | PhosphoSitePlus | |||
T129 | Phosphorylation | score1 | PhosphoSitePlus | |||
K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y146 | Phosphorylation | score1 | PhosphoSitePlus | |||
K152 | Ubiquitination | score1 | PhosphoSitePlus | |||
K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
T192 | Phosphorylation | score1 | PhosphoSitePlus | |||
K196 | Acetylation | score1 | PhosphoSitePlus | |||
K196 | Methylation | score1 | PhosphoSitePlus | |||
K196 | Ubiquitination | score1 | PhosphoSitePlus | |||
K208 | Acetylation | score1 | PhosphoSitePlus | |||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
K238 | Acetylation | score1 | PhosphoSitePlus | |||
K240 | Acetylation | score1 | PhosphoSitePlus | |||
K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
K253 | Acetylation | score1 | PhosphoSitePlus | |||
K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
K309 | Acetylation | score1 | PhosphoSitePlus | |||
T315 | Phosphorylation | score1 | PhosphoSitePlus | |||
K320 | Ubiquitination | score1 | PhosphoSitePlus | |||
K328 | Ubiquitination | score1 | PhosphoSitePlus | |||
K363 | Ubiquitination | score1 | PhosphoSitePlus | |||
K367 | Ubiquitination | score1 | PhosphoSitePlus | |||
K448 | Ubiquitination | score1 | PhosphoSitePlus | |||
C453 | S-Nitrosylation | score0 | dbSNO | 19483679, 26338901 | ||
K469 | Acetylation | score1 | PhosphoSitePlus | |||
K469 | Ubiquitination | score1 | PhosphoSitePlus | |||
T478 | Phosphorylation | score1 | PhosphoSitePlus | |||
K484 | Ubiquitination | score1 | PhosphoSitePlus | |||
K490 | Acetylation | score1 | PhosphoSitePlus | |||
K490 | Ubiquitination | score1 | PhosphoSitePlus | |||
K493 | Acetylation | score1 | PhosphoSitePlus | |||
K493 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S62 | Phosphorylation | score1 | PhosphoSitePlus | |||
K74 | Acetylation | score1 | PhosphoSitePlus | |||
K74 | Ubiquitination | score1 | PhosphoSitePlus | |||
R91 | Methylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
S49 | Phosphorylation | score1 | PhosphoSitePlus | |||
S62 | Phosphorylation | score1 | PhosphoSitePlus | |||
K74 | Acetylation | score1 | PhosphoSitePlus | |||
K74 | Ubiquitination | score1 | PhosphoSitePlus | |||
S88 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y109 | H109 | Biomuta | DOID:363 / uterine cancer [ tcga ] | |
Y146 | H146 | Biomuta | DOID:263 / kidney cancer [ cosmic, tcga ] | |
T192 | S192 | Biomuta | DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ] | |
K196 | E196 | Biomuta | DOID:9256 / colorectal cancer [ tcga ] |