iPTMnet Report for P15153 (RAC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P15153 / RAC2_HUMAN
Protein Name Ras-related C3 botulinum toxin substrate 2 precursor
Gene Name Name: RAC2
Organism Homo sapiens (Human)

PRO ID PR:P15153
DAG View
PRO Name Ras-related C3 botulinum toxin substrate 2 (human)
Definition A Ras-related C3 botulinum toxin substrate 2 that is encoded in the genome of human.
Short Label hRAC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P15153 (RAC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
C6 S-Nitrosylation dbSNO 2212679, 22126794
T17 O-Glycosylation GlyGen 35132862, 24141704, 29351928
C18 Methylation IEDB 31844290
Y32 O-Glycosylation GlyGen 24141704
Y32 Phosphorylation PhosphoSitePlus
S41 O-Glycosylation GlyGen 35132862, 24141704, 29351928
Y64 Phosphorylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
C105 Methylation IEDB 31844290
C105 S-Nitrosylation dbSNO 2212679, 22126794
K116 Ubiquitination PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K123 Methylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K130 Methylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K147 Acetylation PhosphoSitePlus   UniProt 19608861
K147 Ubiquitination PhosphoSitePlus
K153 Acetylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
C157 Methylation IEDB 31844290
T161 Phosphorylation PhosphoSitePlus
R163 Methylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
R174 Methylation IEDB 32357974
C178 Methylation IEDB 31844290
C178 S-Nitrosylation dbSNO 24105792


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C18 R18 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y64 H64 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
C105 F105 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K116 R116 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K116 N116 Biomuta DOID:1324 / lung cancer [ cosmic ]
K130 R130 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K147 M147 Biomuta DOID:1324 / lung cancer [ cosmic ]
T161 I161 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R174 Q174 Biomuta DOID:9256 / colorectal cancer [ cosmic ]