iPTMnet Report for P14784 (IL2RB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P14784 / IL2RB_HUMAN
Protein Name Interleukin-2 receptor subunit beta precursor
Gene Name Name: IL2RB
Synonyms:IL15RB;
Organism Homo sapiens (Human)

PRO ID PR:P14784
DAG View
PRO Name interleukin-2 receptor subunit beta (human)
Definition An interleukin-2 receptor subunit beta that is encoded in the genome of human.
Short Label hIL2RB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P14784 (IL2RB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
N43 N-Glycosylation GlyGen   UniProt 16477002, 24190977
N71 N-Glycosylation GlyGen   UniProt 16477002
T105 Phosphorylation PhosphoSitePlus
N149 N-Glycosylation GlyGen   UniProt 24190977, 16477002, 16293754
T282 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
Y364 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus 7499411, 8700888, 8643566
Y364 Phosphorylation P23458 (JAK1) HPRD 8700888
Y381 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 10214954, 2047859
Y381 Phosphorylation P06239 (LCK) HPRD   phospho.ELM   PhosphoSitePlus 10214954, 2047859
Y384 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 10214954, 2047859
Y384 Phosphorylation P06239 (LCK) HPRD   phospho.ELM   PhosphoSitePlus 10214954, 2047859
Y387 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 10214954, 2047859
Y387 Phosphorylation P06239 (LCK) HPRD   phospho.ELM   PhosphoSitePlus 10214954, 2047859
Y418 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus 10214954
Y418 Phosphorylation P06239 (LCK) HPRD   phospho.ELM   PhosphoSitePlus 10214954
S431 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus
T476 Phosphorylation PhosphoSitePlus 26152718
T476 Phosphorylation P27361 (MAPK3) PhosphoSitePlus 26152718
T476 Phosphorylation P28482 (MAPK1) PhosphoSitePlus 26152718
Y536 Phosphorylation HPRD   IntAct   phospho.ELM   PRO   PhosphoSitePlus 12200137, 10602027, 10214954
Y536 Phosphorylation P06239 (LCK) HPRD   phospho.ELM   PhosphoSitePlus 10214954


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048017 (hIL2RB/SigPep-/Phos:1) pY364,pY418,pY536 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T476 I476 Biomuta DOID:2531 / hematologic cancer [ cosmic ]