iPTMnet Report for P14679 (TYR)
Protein Information
| UniProt AC / UniProt ID | P14679 / TYRO_HUMAN |
| Protein Name | Tyrosinase precursor |
| Gene Name | Name: TYR |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P14679 |
| PRO Name | tyrosinase (human) |
| Definition | A tyrosinase that is encoded in the genome of human. |
| Short Label | hTYR |
| Category | organism-gene |
P14679 (TYR) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| C8 | Methylation | score1 | IEDB | 31844290 | ||
| N86 | N-Glycosylation | score2 | GlyGen | 10713140 | ||
| N290 | N-Glycosylation | score2 | GlyGen | 11069924 | ||
| N371 | N-Glycosylation | score2 | GlyGen | 10713140 | ||
| S523 | Phosphorylation | score3 | neXtProt PhosphoSitePlus Signor | 10347209 | ||
| S523 | Phosphorylation | P05771 (PRKCB) | score3 | neXtProt PhosphoSitePlus Signor | 10347209 | |
| S527 | Phosphorylation | score3 | neXtProt PhosphoSitePlus Signor | 10347209 | ||
| S527 | Phosphorylation | P05771 (PRKCB) | score3 | neXtProt PhosphoSitePlus Signor | 10347209 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S523 | G523 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View