iPTMnet Report for P14678 (SNRPB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P14678 / RSMB_HUMAN
Protein Name Small nuclear ribonucleoprotein-associated proteins B and B'
Gene Name Name: SNRPB
Synonyms:COD,SNRPB1;
Organism Homo sapiens (Human)

PRO ID PR:P14678
DAG View
PRO Name small nuclear ribonucleoprotein-associated proteins B and B' (human)
Definition A small nuclear ribonucleoprotein-associated proteins B and B' that is encoded in the genome of human.
Short Label hSNRPB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P14678 (SNRPB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
K8 Acetylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
Y15 Phosphorylation PhosphoSitePlus
R16 Methylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
K32 Acetylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K36 Acetylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
C43 S-Nitrosylation dbSNO 26338901
C45 S-Nitrosylation dbSNO 26338901
K57 Acetylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
R94 Methylation PhosphoSitePlus
R108 Methylation PhosphoSitePlus   UniProt 24129315
R112 Methylation PhosphoSitePlus   UniProt 24129315
R132 Methylation PhosphoSitePlus
R147 Methylation PhosphoSitePlus
R172 Methylation PhosphoSitePlus
R181 Methylation PhosphoSitePlus
R209 Methylation PhosphoSitePlus
R221 Methylation PhosphoSitePlus
R228 Methylation PhosphoSitePlus
R236 Methylation PhosphoSitePlus
R239 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation HPRD 20068231
Y15 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation HPRD 20068231
Y15 Phosphorylation HPRD 20068231
R221 Methylation PhosphoSitePlus
R228 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S250 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T2 M2 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]
K32 E32 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K88 * Biomuta DOID:1324 / lung cancer [ cosmic ]
R94 L94 Biomuta DOID:1324 / lung cancer [ cosmic ]
R94 P94 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R94 Q94 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:2021 / placenta cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, cosmic, cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R132 L132 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R132 H132 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
R172 H172 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R172 C172 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R181 Q181 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R181 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
R221 Q221 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R221 W221 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R228 Q228 Biomuta DOID:363 / uterine cancer [ icgc ]
R228 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2021 / placenta cancer [ cosmic ]
R236 H236 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ]
R236 C236 Biomuta DOID:263 / kidney cancer [ cosmic ]