iPTMnet Report P14373 TRIM27

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P14373 / TRI27_HUMAN
Protein Name	Zinc finger protein RFP
Gene Name	Name: TRIM27 Synonyms:RFP,RNF76;
Organism	Homo sapiens (Human)

PRO ID	PR:P14373 DAG View
PRO Name	zinc finger protein RFP (human)
Definition	A zinc finger protein RFP that is encoded in the genome of human.
Short Label	hTRIM27
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P14373 (TRIM27) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K79	Ubiquitination		score1	PhosphoSitePlus
	K98	Ubiquitination		score1	PhosphoSitePlus
	K140	Ubiquitination		score1	PhosphoSitePlus
	K151	Ubiquitination		score1	PhosphoSitePlus
	K181	Ubiquitination		score1	PhosphoSitePlus
	K194	Ubiquitination		score1	PhosphoSitePlus
	T269	Phosphorylation		score1	PhosphoSitePlus
	K276	Ubiquitination		score1	PhosphoSitePlus
	K283	Ubiquitination		score1	PhosphoSitePlus
	K292	Ubiquitination		score1	PhosphoSitePlus
	K297	Ubiquitination		score1	PhosphoSitePlus
	K304	Ubiquitination		score1	PhosphoSitePlus
	S341	Phosphorylation		score1	PhosphoSitePlus
	K380	Ubiquitination		score1	PhosphoSitePlus
	K382	Ubiquitination		score1	PhosphoSitePlus
	S493	Phosphorylation		score1	PhosphoSitePlus
	S499	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S341	Phosphorylation		score0	HPRD	19691289
	S483	Phosphorylation		score0	HPRD	20068231
	S493	Phosphorylation		score0	HPRD	20068231
	S499	Phosphorylation		score0	HPRD	20068231

Proteoform PPIs

	Protein 1	Relation	Protein 2	Source	PMID
	PR:P29590-4 (hPML/iso:4)	Interaction	PR:P14373 (hTRIM27)	PRO	9570750
	PR:P29590-4 (hPML/iso:4)	Interaction	PR:P14373 (hTRIM27)	PRO	9570750
	PR:P29590-4 (hPML/iso:4)	Interaction	PR:P14373 (hTRIM27)	PRO	9570750

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K151	T151	Biomuta		DOID:363 / uterine cancer [ tcga ]
K283	*	Biomuta		DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
K297	N297	Biomuta		DOID:11054 / urinary bladder cancer [ tcga ]
K304	R304	Biomuta		DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S483	R483	Biomuta		DOID:363 / uterine cancer [ tcga ]
S483	N483	Biomuta		DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S499	F499	Biomuta		DOID:1612 / breast cancer [ tcga ]