iPTMnet Report for P14373 (TRIM27)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P14373 / TRI27_HUMAN
Protein Name Zinc finger protein RFP
Gene Name Name: TRIM27
Synonyms:RFP,RNF76;
Organism Homo sapiens (Human)

PRO ID PR:P14373
DAG View
PRO Name zinc finger protein RFP (human)
Definition A zinc finger protein RFP that is encoded in the genome of human.
Short Label hTRIM27
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P14373 (TRIM27) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K79 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
T269 Phosphorylation PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S341 Phosphorylation HPRD 19691289
S483 Phosphorylation HPRD 20068231
S493 Phosphorylation HPRD 20068231
S499 Phosphorylation HPRD 20068231


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:P29590-4 (hPML/iso:4) Interaction PR:P14373 (hTRIM27) PRO 9570750


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K151 T151 Biomuta DOID:363 / uterine cancer [ tcga ]
K283 * Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
K297 N297 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
K304 R304 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S483 R483 Biomuta DOID:363 / uterine cancer [ tcga ]
S483 N483 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S499 F499 Biomuta DOID:1612 / breast cancer [ tcga ]