Protein Information

Cytoscape View


UniProt AC / UniProt ID P14314 / GLU2B_HUMAN
Protein Name Glucosidase 2 subunit beta precursor
Gene Name Name: PRKCSH
Synonyms:G19P1;
Organism Homo sapiens (Human)

PRO ID PR:P14314
DAG View
PRO Name glucosidase 2 subunit beta (human)
Definition A glucosidase 2 subunit beta that is encoded in the genome of human.
Short Label hPRKCSH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P14314 (PRKCSH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus   UniProt 26091039
N72 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N79 N-Glycosylation GlyGen 24190977
K83 Methylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
N90 N-Glycosylation GlyGen 24190977
S126 Phosphorylation PhosphoSitePlus
T134 O-Glycosylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus   UniProt 26091039
R177 Methylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K219 Acetylation PhosphoSitePlus
T263 O-Glycosylation GlyGen 30459171
S282 O-Glycosylation GlyGen 23301498, 27114449, 26853435, ...25128556, 29351928, 32119511, 22661428, 29237092
T287 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 27114449, 30459171, ...26853435, 25128556, 29351928, 32119511, 22661428, 29237092
S293 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 27114449, 30459171, ...26853435, 25128556, 29351928, 32119511, 22661428, 29237092
T298 O-Glycosylation GlyGen 23301498, 27114449, 26853435, ...25128556, 29351928, 32119511, 22661428, 29237092
S343 O-Glycosylation GlyGen 30459171
S343 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
T363 O-Glycosylation GlyGen 30459171
K376 Acetylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
Y423 Phosphorylation PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
T448 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
K459 Acetylation PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
N476 N-Glycosylation GlyGen 29741879, 24190977
K487 Ubiquitination PhosphoSitePlus
T494 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R177 W177 Biomuta DOID:10283 / prostate cancer [ cosmic ]
R177 Q177 Biomuta DOID:1612 / breast cancer [ cosmic ]
K196 N196 Biomuta DOID:363 / uterine cancer [ tcga ]
S282 F282 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T287 N287 Biomuta DOID:363 / uterine cancer [ tcga ]
T298 M298 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S349 I349 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S434 L434 Biomuta DOID:4362 / cervical cancer [ tcga ]
S442 F442 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S451 * Biomuta DOID:363 / uterine cancer [ tcga ]
S498 N498 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]