iPTMnet Report for P14174 (MIF)
Protein Information
UniProt AC / UniProt ID | P14174 / MIF_HUMAN |
Protein Name | Macrophage migration inhibitory factor |
Gene Name | Name: MIF Synonyms:GLIF,MMIF; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P14174 |
PRO Name | macrophage migration inhibitory factor (human) |
Definition | A macrophage migration inhibitory factor that is encoded in the genome of human. |
Short Label | hMIF |
Category | organism-gene |
P14174 (MIF) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T8 | Phosphorylation | score1 | PhosphoSitePlus | |||
R12 | Methylation | score1 | PhosphoSitePlus | |||
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y37 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 15592455 | ||
C60 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
K67 | Acetylation | score1 | PhosphoSitePlus | |||
R74 | Methylation | score1 | PhosphoSitePlus | |||
S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
K78 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
C81 | Methylation | score1 | IEDB | 31844290 | ||
C81 | S-Nitrosylation | score0 | dbSNO | 19483679, 24105792, 25040305 | ||
R87 | Methylation | score1 | PhosphoSitePlus | |||
R89 | Methylation | score1 | PhosphoSitePlus | |||
S91 | Phosphorylation | score1 | PhosphoSitePlus | |||
R94 | Methylation | score1 | PhosphoSitePlus | |||
Y99 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y100 | Phosphorylation | score1 | PhosphoSitePlus | |||
S112 | O-Glycosylation | score3 | GlyGen PhosphoSitePlus | 26280537 | ||
T113 | O-Glycosylation | score4 | GlyGen PhosphoSitePlus | 33214551, 34019948, 35083852, ... |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R12 | L12 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
R12 | P12 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S14 | F14 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R74 | H74 | Biomuta | DOID:2174 / ocular cancer [ cosmic ] | |
S75 | F75 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
R89 | P89 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
R89 | H89 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
R94 | M94 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y99 | C99 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |