iPTMnet Report for P14174 (MIF)
Protein Information
| UniProt AC / UniProt ID | P14174 / MIF_HUMAN |
| Protein Name | Macrophage migration inhibitory factor |
| Gene Name | Name: MIF Synonyms:GLIF,MMIF; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P14174 |
| PRO Name | macrophage migration inhibitory factor (human) |
| Definition | A macrophage migration inhibitory factor that is encoded in the genome of human. |
| Short Label | hMIF |
| Category | organism-gene |
P14174 (MIF) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R12 | Methylation | score1 | PhosphoSitePlus | |||
| S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y37 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 15592455 | ||
| C60 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
| K67 | Acetylation | score1 | PhosphoSitePlus | |||
| R74 | Methylation | score1 | PhosphoSitePlus | |||
| S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K78 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C81 | Methylation | score1 | IEDB | 31844290 | ||
| C81 | S-Nitrosylation | score0 | dbSNO | 19483679, 24105792, 25040305 | ||
| R87 | Methylation | score1 | PhosphoSitePlus | |||
| R89 | Methylation | score1 | PhosphoSitePlus | |||
| S91 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R94 | Methylation | score1 | PhosphoSitePlus | |||
| Y99 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y100 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S112 | O-Glycosylation | score3 | GlyGen PhosphoSitePlus | 26280537 | ||
| T113 | O-Glycosylation | score4 | GlyGen PhosphoSitePlus | 33214551, 34019948, 35083852, ... |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R12 | L12 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| R12 | P12 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S14 | F14 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R74 | H74 | Biomuta | DOID:2174 / ocular cancer [ cosmic ] | |
| S75 | F75 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| R89 | P89 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| R89 | H89 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| R94 | M94 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| Y99 | C99 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
DAG View