iPTMnet Report for P13987 (CD59)
Protein Information
UniProt AC / UniProt ID | P13987 / CD59_HUMAN |
Protein Name | CD59 glycoprotein precursor |
Gene Name | Name: CD59 Synonyms:MIC11,MIN1,MIN2,MIN3,MSK21; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P13987 |
PRO Name | CD59 glycoprotein (human) |
Definition | A CD59 glycoprotein that is encoded in the genome of human. |
Short Label | hCD59 |
Category | organism-gene |
P13987 (CD59) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y29 | Phosphorylation | score1 | PhosphoSitePlus | |||
T40 | O-Glycosylation | score1 | GlyGen | 34846842, 30237853 | ||
N43 | N-Glycosylation | score4 | GlyGen UniProt | 30237853, 32125861, 24190977, ... | ||
K63 | Acetylation | score1 | PhosphoSitePlus | |||
K66 | Acetylation | score1 | PhosphoSitePlus | |||
T76 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
T77 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
Y86 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y87 | Phosphorylation | score1 | PhosphoSitePlus | |||
K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
T105 | O-Glycosylation | score1 | GlyGen | 30237853 | ||
S106 | O-Glycosylation | score1 | GlyGen | 30237853 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K63 | E63 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
Y87 | F87 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |