Protein Information

Cytoscape View

UniProt AC / UniProt ID P13984 / T2FB_HUMAN
Protein Name General transcription factor IIF subunit 2
Gene Name Name: GTF2F2
Organism Homo sapiens (Human)

PRO ID PR:P13984
DAG View
PRO Name general transcription factor IIF subunit 2 (human)
Definition A general transcription factor IIF subunit 2 that is encoded in the genome of human.
Short Label hGTF2F2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P13984 (GTF2F2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
T10 Phosphorylation PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
K22 Acetylation PhosphoSitePlus   UniProt 19608861
K22 Ubiquitination PhosphoSitePlus
K25 Sumoylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K33 Acetylation PhosphoSitePlus   UniProt 19608861
K33 Methylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
R37 Methylation PhosphoSitePlus
K42 Acetylation PhosphoSitePlus
K71 Acetylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
S76 Phosphorylation HPRD 20068231
S87 Phosphorylation PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
K137 Acetylation PhosphoSitePlus   UniProt 19608861
K137 Ubiquitination PhosphoSitePlus
S142 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17525332
K147 Ubiquitination PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
K154 Acetylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K236 Sumoylation PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
S248 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16083285, 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S87 I87 Biomuta DOID:3571 / liver cancer [ icgc ]
S142 L142 Biomuta DOID:363 / uterine cancer [ tcga ]
K200 Q200 Biomuta DOID:1909 / melanoma [ icgc, tcga ]