iPTMnet Report for P13798 (APEH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P13798 / ACPH_HUMAN
Protein Name Acylamino-acid-releasing enzyme
Gene Name Name: APEH
Synonyms:D3F15S2,D3S48E,DNF15S2;
Organism Homo sapiens (Human)

PRO ID PR:P13798
DAG View
PRO Name acylamino-acid-releasing enzyme (human)
Definition An acylamino-acid-releasing enzyme that is encoded in the genome of human.
Short Label hAPEH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13798 (APEH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 10395453
S8 Phosphorylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S187 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18767875, ...19664994, 18452278, 18669648, 19690332, 24275569, 19415658, 20068231
K195 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
Y209 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
K664 Ubiquitination PhosphoSitePlus
T665 Phosphorylation PhosphoSitePlus
R676 Methylation PhosphoSitePlus
K681 Methylation PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
T692 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y209 C209 Biomuta DOID:3571 / liver cancer [ cosmic ]
S493 N493 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R676 W676 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]