Protein Information

Cytoscape View


UniProt AC / UniProt ID P13693 / TCTP_HUMAN
Protein Name Translationally-controlled tumor protein
Gene Name Name: TPT1
Organism Homo sapiens (Human)

PRO ID PR:P13693
DAG View
PRO Name translationally-controlled tumor protein (human)
Definition A translationally-controlled tumor protein that is encoded in the genome of human.
Short Label hTPT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13693 (TPT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus   RLIMS-P 25854427
S15 Phosphorylation PhosphoSitePlus   RLIMS-P 25854427
Y18 Phosphorylation PhosphoSitePlus
K19 Acetylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
S37 Phosphorylation RLIMS-P 25854427
T39 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S46 Phosphorylation P53350 (PLK1) phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 17287340, 29719201, 21187478, ...12167714, 18669648, 25854427
S53 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 25854427
S64 Phosphorylation P53350 (PLK1) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12167714, 29719201
T65 Phosphorylation PhosphoSitePlus
Y88 Phosphorylation PhosphoSitePlus
Y91 Phosphorylation PhosphoSitePlus
K93 Acetylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
K97 Acetylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
S98 Phosphorylation RLIMS-P 25854427
K102 Acetylation PhosphoSitePlus
K102 Sumoylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K112 Acetylation PhosphoSitePlus
K112 Sumoylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K130 Acetylation PhosphoSitePlus
K130 Methylation PhosphoSitePlus
K130 Sumoylation PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T39 Phosphorylation HPRD 18669648, 20068231
S46 Phosphorylation P53350 (PLK1) HPRD   PRO 12167714, 18669648, 17287340, ...20068231
S53 Phosphorylation HPRD   PRO 18669648, 20068231
S64 Phosphorylation P53350 (PLK1) HPRD   PRO 12167714
K93 Acetylation PRO
T116 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036126 (hTPT1/Ac:1) acK93 PRO
PR:000036128 (hTPT1/Phos:1) pS53 PRO
PR:000036130 (hTPT1/Phos:2) pS46 PRO
PR:000036132 (hTPT1/Phos:3) pS46,pS64 PRO
PR:000036134 (hTPT1/AcPhos:1) acK93 PRO
PR:000036134 (hTPT1/AcPhos:1) pS53,pS64 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S15 T15 Biomuta DOID:263 / kidney cancer [ cosmic ]
S37 I37 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y88 * Biomuta DOID:3571 / liver cancer [ icgc ]