iPTMnet Report for P13688 (CEACAM1)
Protein Information
| UniProt AC / UniProt ID | P13688 / CEAM1_HUMAN |
| Protein Name | Carcinoembryonic antigen-related cell adhesion molecule 1 precursor |
| Gene Name | Name: CEACAM1 Synonyms:BGP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P13688 |
| PRO Name | carcinoembryonic antigen-related cell adhesion molecule 1 (human) |
| Definition | A carcinoembryonic antigen-related cell adhesion molecule 1 that is encoded in the genome of human. |
| Short Label | hCEACAM1 |
| Category | organism-gene |
DAG ViewP13688 (CEACAM1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T38 | Phosphorylation | score0 | RLIMS-P | 29558679 | ||
| N104 | N-Glycosylation | score2 | GlyGen UniProt | 16335952 | ||
| S106 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| N111 | N-Glycosylation | score2 | GlyGen UniProt | 16335952 | ||
| N115 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N152 | N-Glycosylation | score2 | GlyGen UniProt | 19159218, 24190977 | ||
| N153 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N155 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N197 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| N208 | N-Glycosylation | score2 | GlyGen UniProt | 19159218, 24190977 | ||
| N224 | N-Glycosylation | score2 | GlyGen UniProt | 19159218, 24190977 | ||
| N345 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N351 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N363 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218, 24190977 | ||
| N378 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218, 29391424, ... | ||
| N405 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
| T457 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P Signor | 24302721, 32835655 | ||
| T457 | Phosphorylation | Q13557 (CAMK2D) | score1 | Signor | 24302721 | |
| S461 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S472 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N475 | N-Glycosylation | score1 | GlyGen | 29391424 | ||
| T492 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y493 | Phosphorylation | score4 | IntAct phospho.ELM PhosphoSitePlus Signor UniProt | 7478590, 18424730, 9867848, ... | ||
| Y493 | Phosphorylation | P12931 (SRC) | score1 | Signor | 9867848 | |
| S494 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S508 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11850617 | ||
| S510 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S512 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y520 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus Signor UniProt | 7478590, 18424730, 9867848 | ||
| Y520 | Phosphorylation | P12931 (SRC) | score1 | Signor | 9867848 | |
| S521 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y493 | Phosphorylation | score1 | HPRD | 9867848 | ||
| Y493 | Phosphorylation | P12931 (SRC) | score1 | HPRD | 9867848 | |
| S508 | Phosphorylation | score1 | HPRD | 11850617 | ||
| S508 | Phosphorylation | Q02779 (MAP3K10) | score1 | HPRD | 11850617 | |
| Y520 | Phosphorylation | score1 | HPRD | 9867848 | ||
| Y520 | Phosphorylation | P12931 (SRC) | score1 | HPRD | 9867848 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T457 | Phosphorylation | score2 | PhosphoSitePlus | 24302721 | ||
| T457 | Phosphorylation | Q13557 (CAMK2D) | score2 | PhosphoSitePlus | 24302721 | |
| S459 | Phosphorylation | score2 | PhosphoSitePlus | 24302721 | ||
| S459 | Phosphorylation | Q13557 (CAMK2D) | score2 | PhosphoSitePlus | 24302721 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S344 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S106 | F106 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| N351 | Y351 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| N475 | K475 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| N475 | S475 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| S521 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
