Protein Information

Cytoscape View


UniProt AC / UniProt ID P13646 / K1C13_HUMAN
Protein Name Keratin, type I cytoskeletal 13
Gene Name Name: KRT13
Organism Homo sapiens (Human)

PRO ID PR:P13646
DAG View
PRO Name keratin, type I cytoskeletal 13 (human)
Definition A keratin, type I cytoskeletal 13 that is encoded in the genome of human.
Short Label hKRT13
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13646 (KRT13) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
Y12 Phosphorylation PhosphoSitePlus
R27 Methylation PhosphoSitePlus   UniProt 24129315
R35 Methylation PhosphoSitePlus   UniProt 24129315
Y118 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus
Y194 Phosphorylation PhosphoSitePlus
Y238 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus
R287 Methylation PhosphoSitePlus
R289 Methylation PhosphoSitePlus
T311 Phosphorylation PhosphoSitePlus
T316 Phosphorylation PhosphoSitePlus
T327 Phosphorylation HPRD   PhosphoSitePlus 20068231
S337 Phosphorylation HPRD   PhosphoSitePlus 20068231
S340 Phosphorylation PhosphoSitePlus
T404 Phosphorylation PhosphoSitePlus
Y405 Phosphorylation PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S427 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 21406692, 17287340, ...17081983
S432 Phosphorylation PhosphoSitePlus
T434 Phosphorylation PhosphoSitePlus
T452 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T327 Phosphorylation HPRD 20068231
S337 Phosphorylation HPRD 20068231
S422 Phosphorylation HPRD 20068231
S425 Phosphorylation HPRD 17081983
S427 Phosphorylation HPRD 17287340, 17081983, 19664995
Site PTM Type PTM Enzyme Score Source PMID
R27 Methylation PhosphoSitePlus
K416 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 N7 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
S11 R11 Biomuta DOID:9256 / colorectal cancer [ icgc ]
R35 Q35 Biomuta DOID:363 / uterine cancer [ tcga ]
Y118 C118 Biomuta DOID:1324 / lung cancer [ tcga ]
S144 N144 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc ]
S153 N153 Biomuta DOID:1909 / melanoma [ tcga ]
S153 I153 Biomuta DOID:1909 / melanoma [ cosmic ]
Y156 C156 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
R287 G287 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
R289 H289 Biomuta DOID:3070 / malignant glioma [ tcga ]
R289 G289 Biomuta DOID:2394 / ovarian cancer [ tcga ]
T327 M327 Biomuta DOID:2531 / hematologic cancer [ icgc ]
S337 F337 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S425 G425 Biomuta DOID:2531 / hematologic cancer [ icgc ]
T452 N452 Biomuta DOID:3571 / liver cancer [ icgc ]