iPTMnet Report for P13535 (MYH8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P13535 / MYH8_HUMAN
Protein Name Myosin-8
Gene Name Name: MYH8
Organism Homo sapiens (Human)

PRO ID PR:P13535
DAG View
PRO Name myosin-8 (human)
Definition A myosin-8 that is encoded in the genome of human.
Short Label hMYH8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13535 (MYH8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T63 Phosphorylation PhosphoSitePlus
T73 Phosphorylation HPRD   PhosphoSitePlus 18452278
Y165 Phosphorylation PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus
T200 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
Y353 Phosphorylation PhosphoSitePlus
T356 Phosphorylation PhosphoSitePlus
Y362 Phosphorylation PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
Y413 Phosphorylation PhosphoSitePlus
T415 Phosphorylation PhosphoSitePlus
K416 Acetylation PhosphoSitePlus
Y424 Phosphorylation PhosphoSitePlus
K505 Acetylation PhosphoSitePlus
Y556 Phosphorylation PhosphoSitePlus
Y591 Phosphorylation PhosphoSitePlus
T663 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
S741 Phosphorylation PhosphoSitePlus
K743 Acetylation PhosphoSitePlus
S745 Phosphorylation PhosphoSitePlus
T791 Phosphorylation PhosphoSitePlus
Y819 Phosphorylation PhosphoSitePlus
K834 Acetylation PhosphoSitePlus
K844 Acetylation PhosphoSitePlus
T854 Phosphorylation PhosphoSitePlus
T862 Phosphorylation PhosphoSitePlus
K874 Acetylation PhosphoSitePlus
S951 Phosphorylation PhosphoSitePlus
K954 Acetylation PhosphoSitePlus
K955 Acetylation PhosphoSitePlus
T963 Phosphorylation PhosphoSitePlus
K979 Acetylation PhosphoSitePlus
T982 Phosphorylation PhosphoSitePlus
T991 Phosphorylation PhosphoSitePlus
K994 Acetylation PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus
S1040 Phosphorylation PhosphoSitePlus
K1045 Acetylation PhosphoSitePlus
S1140 Phosphorylation PhosphoSitePlus
S1143 Phosphorylation PhosphoSitePlus
K1169 Ubiquitination PhosphoSitePlus
K1176 Ubiquitination PhosphoSitePlus
K1222 Ubiquitination PhosphoSitePlus
S1236 Phosphorylation PhosphoSitePlus
T1277 Phosphorylation PhosphoSitePlus
S1302 Phosphorylation PhosphoSitePlus
S1338 Phosphorylation PhosphoSitePlus
S1369 Phosphorylation PhosphoSitePlus
T1376 Phosphorylation PhosphoSitePlus
Y1378 Phosphorylation PhosphoSitePlus
T1380 Phosphorylation PhosphoSitePlus
T1386 Phosphorylation PhosphoSitePlus
K1393 Acetylation PhosphoSitePlus
K1394 Acetylation PhosphoSitePlus
K1395 Acetylation PhosphoSitePlus
T1420 Phosphorylation PhosphoSitePlus
Y1463 Phosphorylation PhosphoSitePlus
T1466 Phosphorylation PhosphoSitePlus
S1477 Phosphorylation PhosphoSitePlus
S1479 Phosphorylation PhosphoSitePlus
S1481 Phosphorylation PhosphoSitePlus
T1482 Phosphorylation PhosphoSitePlus
S1513 Phosphorylation PhosphoSitePlus
T1516 Phosphorylation PhosphoSitePlus
S1573 Phosphorylation PhosphoSitePlus
S1602 Phosphorylation PhosphoSitePlus
T1603 Phosphorylation PhosphoSitePlus
Y1646 Phosphorylation PhosphoSitePlus
T1649 Phosphorylation PhosphoSitePlus
S1701 Phosphorylation PhosphoSitePlus
S1713 Phosphorylation PhosphoSitePlus
T1721 Phosphorylation PhosphoSitePlus
T1724 Phosphorylation PhosphoSitePlus
S1725 Phosphorylation PhosphoSitePlus
T1729 Phosphorylation PhosphoSitePlus
K1730 Acetylation PhosphoSitePlus
T1763 Phosphorylation PhosphoSitePlus
K1773 Acetylation PhosphoSitePlus
T1854 Phosphorylation PhosphoSitePlus
Y1855 Phosphorylation PhosphoSitePlus
K1862 Acetylation PhosphoSitePlus
S1918 Phosphorylation PhosphoSitePlus
K1933 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T63 I63 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T356 K356 Biomuta DOID:3571 / liver cancer [ cosmic ]
T356 A356 Biomuta DOID:363 / uterine cancer [ icgc ]
K505 N505 Biomuta DOID:184 / bone cancer [ cosmic ]
Y556 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S741 T741 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S745 F745 Biomuta DOID:4159 / skin cancer [ cosmic ]
K834 E834 Biomuta DOID:4159 / skin cancer [ cosmic ]
T862 S862 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K874 N874 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S951 L951 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K954 N954 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T963 A963 Biomuta DOID:363 / uterine cancer [ icgc ]
K979 N979 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K994 N994 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K1045 N1045 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1143 Y1143 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1277 K1277 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1302 C1302 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1302 F1302 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1369 I1369 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T1380 M1380 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1393 Q1393 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T1420 M1420 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
Y1463 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1463 F1463 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1477 P1477 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1481 N1481 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1513 C1513 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1516 S1516 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1603 M1603 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y1646 C1646 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic ]
S1701 N1701 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1721 I1721 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1724 N1724 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1729 A1729 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K1730 N1730 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T1763 N1763 Biomuta DOID:1324 / lung cancer [ cosmic ]
K1773 N1773 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1862 R1862 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]