iPTMnet Report for P13533 (MYH6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P13533 / MYH6_HUMAN
Protein Name Myosin-6
Gene Name Name: MYH6
Synonyms:MYHCA;
Organism Homo sapiens (Human)

PRO ID PR:P13533
DAG View
PRO Name myosin-6 (human)
Definition A myosin-6 that is encoded in the genome of human.
Short Label hMYH6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13533 (MYH6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
Y162 Phosphorylation PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
T256 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
Y267 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
T379 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
Y411 Phosphorylation PhosphoSitePlus
T413 Phosphorylation PhosphoSitePlus
K414 Acetylation PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
Y423 Phosphorylation PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
T447 Phosphorylation PhosphoSitePlus
K503 Acetylation PhosphoSitePlus
K550 Acetylation PhosphoSitePlus
Y554 Phosphorylation PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
T662 Phosphorylation PhosphoSitePlus
T666 Phosphorylation PhosphoSitePlus
T667 Phosphorylation PhosphoSitePlus
Y717 Phosphorylation PhosphoSitePlus
Y758 Phosphorylation PhosphoSitePlus
K759 Acetylation PhosphoSitePlus
S784 Phosphorylation PhosphoSitePlus
S881 Phosphorylation PhosphoSitePlus
T939 Phosphorylation PhosphoSitePlus
K941 Acetylation PhosphoSitePlus
S950 Phosphorylation PhosphoSitePlus
K953 Acetylation PhosphoSitePlus
K954 Acetylation PhosphoSitePlus
T962 Phosphorylation PhosphoSitePlus
T981 Phosphorylation PhosphoSitePlus
T995 Phosphorylation PhosphoSitePlus
S1039 Phosphorylation PhosphoSitePlus
K1044 Acetylation PhosphoSitePlus
K1045 Acetylation PhosphoSitePlus
K1054 Acetylation PhosphoSitePlus
S1067 Phosphorylation PhosphoSitePlus
T1129 Phosphorylation PhosphoSitePlus
S1139 Phosphorylation PhosphoSitePlus
S1142 Phosphorylation PhosphoSitePlus
S1160 Phosphorylation PhosphoSitePlus
K1167 Acetylation PhosphoSitePlus
T1184 Phosphorylation PhosphoSitePlus
T1190 Phosphorylation PhosphoSitePlus
S1201 Phosphorylation PhosphoSitePlus
S1224 Phosphorylation PhosphoSitePlus
T1234 Phosphorylation PhosphoSitePlus
S1235 Phosphorylation PhosphoSitePlus
Y1261 Phosphorylation PhosphoSitePlus
S1301 Phosphorylation PhosphoSitePlus
T1304 Phosphorylation PhosphoSitePlus
S1309 Phosphorylation PhosphoSitePlus
Y1310 Phosphorylation PhosphoSitePlus
T1311 Phosphorylation PhosphoSitePlus
K1318 Acetylation PhosphoSitePlus
S1337 Phosphorylation PhosphoSitePlus
Y1349 Phosphorylation PhosphoSitePlus
T1353 Phosphorylation PhosphoSitePlus
S1364 Phosphorylation PhosphoSitePlus
S1368 Phosphorylation PhosphoSitePlus
T1375 Phosphorylation PhosphoSitePlus
Y1377 Phosphorylation PhosphoSitePlus
T1379 Phosphorylation PhosphoSitePlus
T1385 Phosphorylation PhosphoSitePlus
K1392 Acetylation PhosphoSitePlus
K1393 Acetylation PhosphoSitePlus
K1394 Acetylation PhosphoSitePlus
K1446 Acetylation PhosphoSitePlus
K1447 Acetylation PhosphoSitePlus
Y1462 Phosphorylation PhosphoSitePlus
S1465 Phosphorylation PhosphoSitePlus
S1467 Phosphorylation PhosphoSitePlus
S1471 Phosphorylation PhosphoSitePlus
S1472 Phosphorylation PhosphoSitePlus
S1478 Phosphorylation PhosphoSitePlus
S1480 Phosphorylation PhosphoSitePlus
T1481 Phosphorylation PhosphoSitePlus
Y1490 Phosphorylation PhosphoSitePlus
S1493 Phosphorylation PhosphoSitePlus
T1499 Phosphorylation PhosphoSitePlus
K1501 Acetylation PhosphoSitePlus
K1589 Acetylation PhosphoSitePlus
S1598 Phosphorylation PhosphoSitePlus
T1601 Phosphorylation PhosphoSitePlus
S1602 Phosphorylation PhosphoSitePlus
S1609 Phosphorylation PhosphoSitePlus
S1632 Phosphorylation PhosphoSitePlus
S1647 Phosphorylation PhosphoSitePlus
S1650 Phosphorylation PhosphoSitePlus
S1712 Phosphorylation PhosphoSitePlus
S1720 Phosphorylation PhosphoSitePlus
T1723 Phosphorylation PhosphoSitePlus
S1724 Phosphorylation PhosphoSitePlus
K1729 Acetylation PhosphoSitePlus
T1762 Phosphorylation PhosphoSitePlus
K1772 Acetylation PhosphoSitePlus
K1786 Acetylation PhosphoSitePlus
K1808 Acetylation PhosphoSitePlus
K1811 Acetylation PhosphoSitePlus
K1812 Acetylation PhosphoSitePlus
K1833 Acetylation PhosphoSitePlus
T1853 Phosphorylation PhosphoSitePlus
Y1854 Phosphorylation PhosphoSitePlus
K1860 Acetylation PhosphoSitePlus
T1893 Phosphorylation PhosphoSitePlus
S1896 Phosphorylation PhosphoSitePlus
S1917 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K247 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y387 C387 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y423 C423 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y423 * Biomuta DOID:3571 / liver cancer [ cosmic ]
T442 M442 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T447 I447 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K503 R503 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S650 L650 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
K941 N941 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K953 N953 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1039 C1039 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1039 F1039 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1045 N1045 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1067 G1067 Biomuta DOID:184 / bone cancer [ cosmic ]
S1142 Y1142 Biomuta DOID:363 / uterine cancer [ icgc ]
T1184 M1184 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K1318 N1318 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1337 L1337 Biomuta DOID:363 / uterine cancer [ icgc ]
S1368 L1368 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1379 A1379 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T1379 K1379 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1379 M1379 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y1462 C1462 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1465 L1465 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1493 F1493 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S1602 F1602 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1647 I1647 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1720 F1720 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1724 G1724 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T1762 P1762 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1762 M1762 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1893 I1893 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1917 Y1917 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]