iPTMnet Report for P13521 (SCG2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P13521 / SCG2_HUMAN
Protein Name Secretogranin-2 precursor
Gene Name Name: SCG2
Synonyms:CHGC;
Organism Homo sapiens (Human)

PRO ID PR:P13521
DAG View
PRO Name secretogranin-2 (human)
Definition A secretogranin-2 that is encoded in the genome of human.
Short Label hSCG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13521 (SCG2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S104 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
Y452 Phosphorylation PhosphoSitePlus
Y457 Phosphorylation PhosphoSitePlus
Y468 Phosphorylation PhosphoSitePlus
Y494 Phosphorylation PhosphoSitePlus
Y507 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
S532 Phosphorylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus
Y596 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S104 L104 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S285 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y349 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S521 A521 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S556 F556 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y596 H596 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]