Protein Information

Cytoscape View


UniProt AC / UniProt ID P13489 / RINI_HUMAN
Protein Name Ribonuclease inhibitor
Gene Name Name: RNH1
Synonyms:PRI,RNH;
Organism Homo sapiens (Human)

PRO ID PR:P13489
DAG View
PRO Name ribonuclease inhibitor (human)
Definition A ribonuclease inhibitor that is encoded in the genome of human.
Short Label hRNH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13489 (RNH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378, 22223895
S2 Phosphorylation HPRD   PhosphoSitePlus 20068231
S7 Phosphorylation PhosphoSitePlus
C38 S-Nitrosylation dbSNO 20140087, 22178444
K46 Ubiquitination PhosphoSitePlus
C75 S-Nitrosylation dbSNO 26338901, 22178444
T82 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 20068231
S84 Phosphorylation PhosphoSitePlus
C85 S-Nitrosylation dbSNO 26338901, 22178444
K86 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus   UniProt 19690332
T98 Phosphorylation PhosphoSitePlus
K169 Acetylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
S225 Phosphorylation HPRD   PhosphoSitePlus 20068231
K226 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
C248 S-Nitrosylation dbSNO 20140087, 22178444
K283 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
C409 S-Nitrosylation dbSNO 22178444
K452 Ubiquitination PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 C7 Biomuta DOID:1612 / breast cancer [ icgc ]
K205 R205 Biomuta DOID:263 / kidney cancer [ tcga ]
K205 N205 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]