iPTMnet Report for P13473 (LAMP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P13473 / LAMP2_HUMAN
Protein Name Lysosome-associated membrane glycoprotein 2 precursor
Gene Name Name: LAMP2
Organism Homo sapiens (Human)

PRO ID PR:P13473
DAG View
PRO Name lysosome-associated membrane glycoprotein 2 (human)
Definition A lysosome-associated membrane glycoprotein 2 that is encoded in the genome of human.
Short Label hLAMP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13473 (LAMP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N32 N-Glycosylation GlyGen   UniProt 16335952, 29741879
N38 N-Glycosylation GlyGen   UniProt 16335952, 29741879
N49 N-Glycosylation GlyGen   UniProt 16335952, 24190977, 23090970, ...29391424, 29741879, 12754519
T57 O-Glycosylation GlyGen 30620550
N58 N-Glycosylation GlyGen   UniProt 29741879, 24190977, 8323299
T63 Phosphorylation PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
N75 N-Glycosylation GlyGen   UniProt 29741879, 24190977, 8323299
N101 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 24190977, ...23090970, 29391424, 29741879, 12754519
N123 N-Glycosylation GlyGen   UniProt 16335952, 29741879, 19159218
N179 N-Glycosylation GlyGen   UniProt 8323299
T181 O-Glycosylation GlyGen 8323299
T194 O-Glycosylation GlyGen 25813380
S195 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 8323299, 25813380, 23584533
T196 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 25813380, 8323299
T200 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 25813380, 8323299
T203 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 25813380, 8323299
T204 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 8323299, 25813380, 23584533
S207 O-Glycosylation GlyGen   UniProt 8323299, 25813380
T209 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 25813380, 8323299
T210 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23301498, 28411811, 34725712, ...25813380, 34019948, 35132862, 23584533, 8323299, 36240223
T211 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 8323299, 25813380, 23584533
T211 Phosphorylation PhosphoSitePlus
T213 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 8323299, 23584533
T213 Phosphorylation PhosphoSitePlus
N229 N-Glycosylation GlyGen   UniProt 8323299, 23345538
N242 N-Glycosylation GlyGen   UniProt 29741879, 8323299
N257 N-Glycosylation GlyGen   UniProt 16335952, 34089345, 19159218, ...24190977, 23090970, 29391424, 29741879, 29671580
S267 Phosphorylation PhosphoSitePlus
T269 Phosphorylation PhosphoSitePlus
N275 N-Glycosylation GlyGen   UniProt 29741879, 29671580, 29391424, ...8323299
Y281 Phosphorylation PhosphoSitePlus
R293 Methylation PhosphoSitePlus
N300 N-Glycosylation GlyGen   UniProt 8323299, 29741879
Y304 Phosphorylation PhosphoSitePlus
N307 N-Glycosylation GlyGen   UniProt 8323299
S309 Phosphorylation PhosphoSitePlus
N317 N-Glycosylation GlyGen   UniProt 8323299
N356 N-Glycosylation GlyGen   UniProt 34089345, 19159218, 24190977, ...23090970, 29391424, 29741879
T358 O-Glycosylation GlyGen 23301498, 28411811, 34725712, ...34019948, 35132862, 36240223
Site PTM Type PTM Enzyme Score Source PMID
N49 N-Glycosylation PRO 29741879
N58 N-Glycosylation PRO 29741879
N229 N-Glycosylation PRO 23345538
N257 N-Glycosylation PRO 29671580
S267 Phosphorylation HPRD 20068231
T269 Phosphorylation HPRD 20068231
N275 N-Glycosylation PRO 29741879, 29671580
Y281 Phosphorylation HPRD 20068231
N356 N-Glycosylation PRO 29741879
Site PTM Type PTM Enzyme Score Source PMID
S267 Phosphorylation HPRD 20068231
T269 Phosphorylation HPRD 20068231
Y281 Phosphorylation HPRD 20068231
K402 Ubiquitination PhosphoSitePlus
Y407 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T194 P194 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T196 I196 Biomuta DOID:4159 / skin cancer [ cosmic ]
T269 A269 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R293 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R293 Q293 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ cosmic, icgc ]