iPTMnet Report P13056 NR2C1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P13056 / NR2C1_HUMAN
Protein Name	Nuclear receptor subfamily 2 group C member 1
Gene Name	Name: NR2C1 Synonyms:TR2;
Organism	Homo sapiens (Human)

PRO ID	PR:P13056 DAG View
PRO Name	nuclear receptor subfamily 2 group C member 1 (human)
Definition	A nuclear receptor subfamily 2 group C member 1 that is encoded in the genome of human.
Short Label	hNR2C1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P13056 (NR2C1) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K42	Ubiquitination		score1	PhosphoSitePlus
	T53	Phosphorylation		score1	PhosphoSitePlus
	K56	Ubiquitination		score1	PhosphoSitePlus
	S64	Phosphorylation		score2	IEDB PhosphoSitePlus	32387766
	T98	Phosphorylation		score1	PhosphoSitePlus
	K119	Ubiquitination		score1	PhosphoSitePlus
	S148	O-Glycosylation		score1	GlyGen	30379171
	K188	Ubiquitination		score1	PhosphoSitePlus
	K196	Acetylation		score1	PhosphoSitePlus
	S215	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 23186163
	T218	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	18669648
	T220	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648
	Y392	Phosphorylation		score1	PhosphoSitePlus
	K523	Ubiquitination		score1	PhosphoSitePlus
	K538	Ubiquitination		score1	PhosphoSitePlus
	S581	O-Glycosylation		score1	GlyGen	30379171

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S215	Phosphorylation		score0	HPRD	18669648, 18452278
	T218	Phosphorylation		score0	HPRD	18669648, 20068231
	T220	Phosphorylation		score0	HPRD	18669648

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S215	Phosphorylation		score0	HPRD	18669648, 18452278
	T218	Phosphorylation		score0	HPRD	18669648, 20068231
	T220	Phosphorylation		score0	HPRD	18669648

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S148	L148	Biomuta		DOID:4159 / skin cancer [ cosmic ]