Protein Information

Cytoscape View


UniProt AC / UniProt ID P13051 / UNG_HUMAN
Protein Name Uracil-DNA glycosylase
Gene Name Name: UNG
Synonyms:DGU,UNG1;
Organism Homo sapiens (Human)

PRO ID PR:P13051
DAG View
PRO Name uracil-DNA glycosylase (human)
Definition A uracil-DNA glycosylase that is encoded in the genome of human.
Short Label hUNG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13051 (UNG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Acetylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
T6 Phosphorylation phospho.ELM   PhosphoSitePlus 15327777
Y8 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S12 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 18220336, 18847512, ...18669648, 18079698, 20068231
S14 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 18220336, 18669648, ...18079698, 19690332, 20068231
S23 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 23186163, 17081983, ...18669648, 18079698, 19690332, 20068231
T31 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K49 Ubiquitination PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
T60 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 17287340, 17081983, ...15302935, 18669648, 18079698, 23186163, 27875297, 19690332, 20068231
S63 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17287340
S64 Phosphorylation P06493 (CDK1) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 18234856, 18669648, ...18079698, 19690332
S67 Phosphorylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
Y125 Phosphorylation PhosphoSitePlus
T126 Phosphorylation phospho.ELM   PhosphoSitePlus 15327777
Y128 Phosphorylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
Y284 Phosphorylation PhosphoSitePlus
K295 Acetylation PhosphoSitePlus   UniProt 19608861
K295 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation HPRD 18669648, 20068231
S14 Phosphorylation HPRD 18669648, 19664995, 20068231
S23 Phosphorylation HPRD 19413330, 17081983, 18452278, ...19651622, 18669648, 20068231
T31 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S40 Phosphorylation HPRD 17081983
T60 Phosphorylation HPRD 19413330, 17287340, 16964243, ...15302935, 19664995, 18452278, 19651622, 18669648, 20068231
S63 Phosphorylation HPRD 19651622, 18669648, 17287340, ...17081983, 20068231
S64 Phosphorylation HPRD 19413330, 17081983, 19664995, ...18452278, 19651622, 18669648, 20068231
S67 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation PhosphoSitePlus
T51 Phosphorylation HPRD 19413330, 17287340, 16964243, ...15302935, 19664995, 18452278, 19651622, 18669648, 20068231
S54 Phosphorylation HPRD 19651622, 18669648, 17287340, ...17081983, 20068231
S55 Phosphorylation HPRD 19413330, 17081983, 19664995, ...18452278, 19651622, 18669648, 20068231
S58 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K49 N49 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K78 N78 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y128 H128 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
T188 I188 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]