iPTMnet Report for P13010 (XRCC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P13010 / XRCC5_HUMAN
Protein Name X-ray repair cross-complementing protein 5
Gene Name Name: XRCC5
Synonyms:G22P2;
Organism Homo sapiens (Human)

PRO ID PR:P13010
DAG View
PRO Name X-ray repair cross-complementing protein 5 (human)
Definition An X-ray repair cross-complementing protein 5 that is encoded in the genome of human.
Short Label hXRCC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13010 (XRCC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C13 Methylation IEDB 31844290
S21 O-Glycosylation GlyGen 34846842
S23 O-Glycosylation GlyGen 34846842
K36 Ubiquitination PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
K51 Sumoylation PhosphoSitePlus
Y74 Phosphorylation RLIMS-P 29226073
S102 Phosphorylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
R141 Methylation PhosphoSitePlus
K144 Acetylation PhosphoSitePlus   UniProt 19608861
K144 Ubiquitination PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
K155 Acetylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
C157 Methylation IEDB 31844290
K171 Ubiquitination PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
K195 Acetylation PhosphoSitePlus
K195 Sumoylation PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K209 Methylation PhosphoSitePlus
Y225 Phosphorylation PhosphoSitePlus
K233 Acetylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
C235 Methylation IEDB 31844290
C235 S-Nitrosylation dbSNO 19483679
K238 Ubiquitination PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
C249 S-Nitrosylation dbSNO 20140087, 22178444
S255 Phosphorylation PhosphoSitePlus   UniProt 23186163
S258 Phosphorylation PhosphoSitePlus   UniProt 23186163
K265 Acetylation PhosphoSitePlus   UniProt 19608861
K265 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K285 Sumoylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
Y295 Phosphorylation PhosphoSitePlus
C296 S-Nitrosylation dbSNO 19483679
K307 Sumoylation PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus   UniProt 23186163
S324 Phosphorylation PhosphoSitePlus
K325 Sumoylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K332 Acetylation PhosphoSitePlus   UniProt 19608861
K332 Methylation PhosphoSitePlus
K332 Sumoylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K334 Methylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
K338 Acetylation PhosphoSitePlus
K338 Sumoylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
C339 Methylation IEDB 31844290
C339 S-Nitrosylation dbSNO 19483679
S341 Phosphorylation PhosphoSitePlus
C346 S-Nitrosylation dbSNO 19483679
K347 Ubiquitination PhosphoSitePlus
K363 Acetylation PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
S378 Phosphorylation HPRD   PhosphoSitePlus 18452278
S379 Phosphorylation HPRD   PhosphoSitePlus 18452278
K399 Acetylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
K443 Acetylation PhosphoSitePlus
K443 Sumoylation PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K466 Acetylation PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
T472 Phosphorylation PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
C493 Methylation IEDB 31844290
C493 S-Nitrosylation dbSNO 19483679, 22178444
T523 Phosphorylation PhosphoSitePlus
T524 Phosphorylation PhosphoSitePlus
K525 Ubiquitination PhosphoSitePlus
S526 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
K532 Acetylation PhosphoSitePlus
K532 Sumoylation PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
K534 Acetylation PhosphoSitePlus
K534 Sumoylation PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
T535 Phosphorylation PhosphoSitePlus   UniProt 23186163
K543 Acetylation PhosphoSitePlus
K543 Sumoylation PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
K565 Acetylation PhosphoSitePlus
K565 Sumoylation PhosphoSitePlus
K565 Ubiquitination PhosphoSitePlus
K566 Acetylation PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
K568 Sumoylation PhosphoSitePlus
T569 Phosphorylation PhosphoSitePlus
S577 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 10026262, 15941674, 24275569, ...29226073
S577 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 10026262, 15941674
S579 Phosphorylation UniProt 10026262
S580 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 10026262, 15941674, 29226073
S580 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 10026262, 15941674
S585 Phosphorylation PhosphoSitePlus
T629 Phosphorylation PhosphoSitePlus
C638 Methylation IEDB 31844290
R640 Methylation PhosphoSitePlus
K648 Acetylation PhosphoSitePlus
K648 Ubiquitination PhosphoSitePlus
K660 Acetylation PhosphoSitePlus   UniProt 19608861
K660 Methylation PhosphoSitePlus
K660 Sumoylation PhosphoSitePlus
K660 Ubiquitination PhosphoSitePlus
K665 Acetylation PhosphoSitePlus   UniProt 19608861
K665 Ubiquitination PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus
K702 Acetylation PhosphoSitePlus
K702 Methylation PhosphoSitePlus
K702 Sumoylation PhosphoSitePlus
K702 Ubiquitination PhosphoSitePlus
K703 Acetylation PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
S712 Phosphorylation HPRD   PhosphoSitePlus 18452278
T715 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 10026262, 15941674, 29226073
T715 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 10026262, 15941674


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P15374 (UCHL3) S75 P13010 (XRCC5) unknown eFIP 30559450