iPTMnet Report for P12956 (XRCC6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P12956 / XRCC6_HUMAN
Protein Name X-ray repair cross-complementing protein 6
Gene Name Name: XRCC6
Synonyms:G22P1;
Organism Homo sapiens (Human)

PRO ID PR:P12956
DAG View
PRO Name X-ray repair cross-complementing protein 6 (human)
Definition An X-ray repair cross-complementing protein 6 that is encoded in the genome of human.
Short Label hXRCC6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12956 (XRCC6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22223895
S2 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23186163, 27402161
S6 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 10026262, 28163277, 15941674
S6 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 10026262, 15941674
Y7 Phosphorylation PhosphoSitePlus
Y8 Phosphorylation PhosphoSitePlus
K9 Sumoylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 26337656, 23186163
S27 Phosphorylation P78527 (PRKDC) PhosphoSitePlus 26337656
S27 Phosphorylation Q13315 (ATM) PhosphoSitePlus 26337656
Y30 Phosphorylation PhosphoSitePlus
K31 Acetylation PhosphoSitePlus   UniProt 19608861
K31 Sumoylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus 26337656
S33 Phosphorylation P78527 (PRKDC) PhosphoSitePlus 26337656
S33 Phosphorylation Q13315 (ATM) PhosphoSitePlus 26337656
S37 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S45 Phosphorylation PhosphoSitePlus
S51 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 10026262, 9362500, 28163277
S51 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 10026262, 9362500
S53 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
T90 Phosphorylation PhosphoSitePlus
K92 Acetylation PhosphoSitePlus
K92 Methylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K100 Acetylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
K114 Acetylation PhosphoSitePlus
K114 Methylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K123 Methylation PhosphoSitePlus
K123 Sumoylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
R194 Methylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K207 Methylation PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
S222 Phosphorylation phospho.ELM   PhosphoSitePlus 16097034
R230 Methylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
R244 Methylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K282 Acetylation PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K287 Acetylation PhosphoSitePlus
K287 Sumoylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus
K297 Sumoylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
R301 Methylation PhosphoSitePlus
T302 Phosphorylation PhosphoSitePlus
S306 O-Glycosylation GlyGen 27655845, 35008409, 30444036, ...35138101, 30397120, 34725712, 33214551, 34019948, 35083852, 22967762, 32119511, 29237092
S306 Phosphorylation PhosphoSitePlus   UniProt 23186163
S314 Phosphorylation PhosphoSitePlus
K317 Acetylation PhosphoSitePlus
K317 Sumoylation PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
R318 Methylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
Y322 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
K331 Acetylation PhosphoSitePlus   UniProt 19608861
K331 Sumoylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K338 Acetylation PhosphoSitePlus   UniProt 19608861
K338 Sumoylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
C389 Methylation IEDB 31844290
K392 Acetylation PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
T401 Phosphorylation PhosphoSitePlus
K424 Sumoylation PhosphoSitePlus
T428 Phosphorylation PhosphoSitePlus
K443 Sumoylation PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
K445 Ubiquitination PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 18847512, ...20068231
T455 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
K461 Acetylation PhosphoSitePlus   UniProt 19608861
K461 Ubiquitination PhosphoSitePlus
K463 Ubiquitination PhosphoSitePlus
K468 Acetylation PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
R474 Methylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus   UniProt 18669648, 21851590, 23186163
S477 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
K510 Sumoylation PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
K526 Acetylation PhosphoSitePlus
K526 Sumoylation PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
Y530 Phosphorylation PhosphoSitePlus   RLIMS-P+ 27998981
Y530 Phosphorylation P12931 (SRC) RLIMS-P+ 27998981
Y534 Phosphorylation PhosphoSitePlus
K539 Acetylation PhosphoSitePlus
K539 Sumoylation PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
T541 Phosphorylation PhosphoSitePlus
K542 Acetylation PhosphoSitePlus
K544 Acetylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus   UniProt 20068231
K553 Acetylation PhosphoSitePlus
K553 Ubiquitination PhosphoSitePlus
K556 Acetylation PhosphoSitePlus
K556 Sumoylation PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus   UniProt 23186163
K565 Ubiquitination PhosphoSitePlus
K570 Acetylation PhosphoSitePlus
K570 Methylation PhosphoSitePlus
K570 Ubiquitination PhosphoSitePlus
K575 Acetylation PhosphoSitePlus
K575 Ubiquitination PhosphoSitePlus
T577 Phosphorylation PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
Y588 Phosphorylation PhosphoSitePlus
K591 Ubiquitination PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
K595 Ubiquitination PhosphoSitePlus
K596 Ubiquitination PhosphoSitePlus
T604 Phosphorylation PhosphoSitePlus
K605 Acetylation PhosphoSitePlus
K605 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 20068231
S27 Phosphorylation HPRD 15302935, 18452278
S37 Phosphorylation HPRD 15302935
T170 Phosphorylation HPRD 20068231
T292 Phosphorylation HPRD 20068230
S306 Phosphorylation HPRD 18669648, 20068231
T307 Phosphorylation HPRD 18669648
T455 Phosphorylation HPRD 17322306, 19413330, 19664994, ...19664995, 20068231
S550 Phosphorylation HPRD 20068231
S552 Phosphorylation HPRD 20068231
T577 Phosphorylation HPRD 20068231