iPTMnet Report for P12883 (MYH7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P12883 / MYH7_HUMAN
Protein Name Myosin-7
Gene Name Name: MYH7
Synonyms:MYHCB;
Organism Homo sapiens (Human)

PRO ID PR:P12883
DAG View
PRO Name myosin-7 (human)
Definition A myosin-7 that is encoded in the genome of human.
Short Label hMYH7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12883 (MYH7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
Y15 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
K34 Acetylation PhosphoSitePlus
K35 Acetylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
T63 Phosphorylation PhosphoSitePlus
Y65 Phosphorylation PhosphoSitePlus
T70 Phosphorylation PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
K129 Acetylation PhosphoSitePlus
Y162 Phosphorylation PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
K213 Acetylation PhosphoSitePlus
T215 Phosphorylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K363 Acetylation PhosphoSitePlus
T378 Phosphorylation PhosphoSitePlus
Y386 Phosphorylation PhosphoSitePlus
Y410 Phosphorylation PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
K413 Acetylation PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus
K429 Acetylation PhosphoSitePlus
T441 Phosphorylation HPRD   PhosphoSitePlus 20068231
T446 Phosphorylation PhosphoSitePlus
T449 Phosphorylation HPRD 20068231
K502 Acetylation PhosphoSitePlus
K549 Acetylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
Y582 Phosphorylation PhosphoSitePlus
Y588 Phosphorylation PhosphoSitePlus
Y609 Phosphorylation PhosphoSitePlus
Y624 Phosphorylation PhosphoSitePlus
T660 Phosphorylation PhosphoSitePlus
T678 Phosphorylation PhosphoSitePlus
S680 Phosphorylation PhosphoSitePlus
Y715 Phosphorylation PhosphoSitePlus
S738 Phosphorylation PhosphoSitePlus
Y756 Phosphorylation PhosphoSitePlus
K757 Acetylation PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
T786 Phosphorylation PhosphoSitePlus
S810 Phosphorylation PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus
S851 Phosphorylation PhosphoSitePlus
K853 Acetylation PhosphoSitePlus
T857 Phosphorylation PhosphoSitePlus
K865 Acetylation PhosphoSitePlus
S866 Phosphorylation HPRD   PhosphoSitePlus 20068231
S879 Phosphorylation PhosphoSitePlus
T937 Phosphorylation PhosphoSitePlus
K939 Acetylation PhosphoSitePlus
K942 Acetylation PhosphoSitePlus
S948 Phosphorylation PhosphoSitePlus
K951 Acetylation PhosphoSitePlus
T960 Phosphorylation PhosphoSitePlus
T979 Phosphorylation PhosphoSitePlus
T993 Phosphorylation PhosphoSitePlus
T1019 Phosphorylation PhosphoSitePlus
S1037 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
K1042 Acetylation PhosphoSitePlus
K1043 Acetylation PhosphoSitePlus
K1052 Acetylation PhosphoSitePlus
S1065 Phosphorylation PhosphoSitePlus
S1102 O-Glycosylation PhosphoSitePlus
S1102 Phosphorylation PhosphoSitePlus
K1106 Acetylation PhosphoSitePlus
K1107 Acetylation PhosphoSitePlus
T1127 Phosphorylation PhosphoSitePlus
S1137 Phosphorylation PhosphoSitePlus
S1140 Phosphorylation PhosphoSitePlus
S1158 Phosphorylation PhosphoSitePlus
K1165 Acetylation PhosphoSitePlus
T1182 Phosphorylation PhosphoSitePlus
T1188 Phosphorylation PhosphoSitePlus
K1195 Acetylation PhosphoSitePlus
S1199 Phosphorylation PhosphoSitePlus
S1222 Phosphorylation PhosphoSitePlus
T1232 Phosphorylation PhosphoSitePlus
S1233 Phosphorylation PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus
T1266 Phosphorylation PhosphoSitePlus
S1269 Phosphorylation PhosphoSitePlus
T1274 Phosphorylation PhosphoSitePlus
S1275 Phosphorylation PhosphoSitePlus
T1282 O-Glycosylation GlyGen 23271734, 30620550
T1282 Phosphorylation PhosphoSitePlus
S1288 Phosphorylation PhosphoSitePlus
S1299 O-Glycosylation PhosphoSitePlus
S1299 Phosphorylation PhosphoSitePlus
T1302 Phosphorylation PhosphoSitePlus
K1305 Acetylation PhosphoSitePlus
T1307 Phosphorylation PhosphoSitePlus
Y1308 Phosphorylation PhosphoSitePlus
T1309 Phosphorylation PhosphoSitePlus
K1316 Acetylation PhosphoSitePlus
K1324 Methylation PhosphoSitePlus
S1335 Phosphorylation PhosphoSitePlus
Y1347 Phosphorylation PhosphoSitePlus
T1351 Phosphorylation PhosphoSitePlus
S1362 Phosphorylation PhosphoSitePlus
S1366 Phosphorylation PhosphoSitePlus
T1373 Phosphorylation PhosphoSitePlus
Y1375 Phosphorylation PhosphoSitePlus
T1377 Phosphorylation PhosphoSitePlus
T1383 Phosphorylation PhosphoSitePlus
K1390 Acetylation PhosphoSitePlus
K1391 Acetylation PhosphoSitePlus
K1392 Acetylation PhosphoSitePlus
S1412 Phosphorylation PhosphoSitePlus
S1413 Phosphorylation PhosphoSitePlus
K1444 Acetylation PhosphoSitePlus
K1445 Acetylation PhosphoSitePlus
Y1460 Phosphorylation PhosphoSitePlus
S1463 Phosphorylation PhosphoSitePlus
S1465 Phosphorylation PhosphoSitePlus
S1469 Phosphorylation PhosphoSitePlus
S1470 Phosphorylation PhosphoSitePlus
S1476 Phosphorylation PhosphoSitePlus
S1478 Phosphorylation PhosphoSitePlus
T1479 Phosphorylation PhosphoSitePlus
Y1488 Phosphorylation PhosphoSitePlus
S1491 Phosphorylation PhosphoSitePlus
T1497 Phosphorylation PhosphoSitePlus
K1499 Acetylation PhosphoSitePlus
S1510 Phosphorylation PhosphoSitePlus
T1513 Phosphorylation PhosphoSitePlus
S1518 Phosphorylation PhosphoSitePlus
S1519 Phosphorylation PhosphoSitePlus
T1522 Phosphorylation PhosphoSitePlus
S1542 Phosphorylation PhosphoSitePlus
S1550 Phosphorylation PhosphoSitePlus
K1587 Acetylation PhosphoSitePlus
S1596 O-Glycosylation PhosphoSitePlus
S1596 Phosphorylation PhosphoSitePlus
T1599 Phosphorylation PhosphoSitePlus
S1600 Phosphorylation PhosphoSitePlus
T1605 Phosphorylation PhosphoSitePlus
S1607 Phosphorylation PhosphoSitePlus
S1630 Phosphorylation PhosphoSitePlus
S1645 Phosphorylation PhosphoSitePlus
S1648 Phosphorylation PhosphoSitePlus
S1710 O-Glycosylation PhosphoSitePlus
S1710 Phosphorylation PhosphoSitePlus
S1718 Phosphorylation PhosphoSitePlus
T1721 Phosphorylation PhosphoSitePlus
S1722 Phosphorylation PhosphoSitePlus
K1727 Acetylation PhosphoSitePlus
S1735 Phosphorylation PhosphoSitePlus
T1739 Phosphorylation PhosphoSitePlus
T1760 Phosphorylation PhosphoSitePlus
K1770 Acetylation PhosphoSitePlus
K1784 Acetylation PhosphoSitePlus
K1806 Acetylation PhosphoSitePlus
K1809 Acetylation PhosphoSitePlus
K1810 Acetylation PhosphoSitePlus
K1831 Acetylation PhosphoSitePlus
K1848 Ubiquitination PhosphoSitePlus
T1851 Phosphorylation PhosphoSitePlus
Y1852 Phosphorylation PhosphoSitePlus
T1854 Phosphorylation PhosphoSitePlus
K1859 Acetylation PhosphoSitePlus
T1891 Phosphorylation PhosphoSitePlus
S1894 Phosphorylation PhosphoSitePlus
S1915 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 L4 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
Y15 C15 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T60 A60 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T70 I70 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
T70 A70 Biomuta DOID:363 / uterine cancer [ icgc ]
S173 F173 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S210 N210 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T215 I215 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T255 K255 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S260 Y260 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S260 F260 Biomuta DOID:1612 / breast cancer [ cosmic ]
K363 N363 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y386 * Biomuta [ cosmic ]
T446 P446 Biomuta DOID:1319 / brain cancer [ cosmic ]
K549 E549 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S560 F560 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
Y582 C582 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S680 F680 Biomuta DOID:4159 / skin cancer [ cosmic ]
S680 Y680 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S738 N738 Biomuta DOID:4159 / skin cancer [ cosmic ]
T786 M786 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S810 Y810 Biomuta DOID:1324 / lung cancer [ cosmic ]
T857 A857 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K865 R865 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S866 F866 Biomuta DOID:4159 / skin cancer [ cosmic ]
S879 F879 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T937 A937 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
T979 R979 Biomuta DOID:1324 / lung cancer [ cosmic ]
T993 I993 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1065 G1065 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S1102 N1102 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K1106 N1106 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1107 N1107 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1140 Y1140 Biomuta DOID:363 / uterine cancer [ icgc ]
S1158 F1158 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1261 N1261 Biomuta [ cosmic ]
S1275 C1275 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1275 N1275 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1282 I1282 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1288 Y1288 Biomuta DOID:363 / uterine cancer [ icgc ]
T1302 A1302 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1335 L1335 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1351 M1351 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S1362 F1362 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1366 A1366 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1366 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T1373 S1373 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y1375 H1375 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T1377 M1377 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T1383 A1383 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1391 M1391 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1413 L1413 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1445 N1445 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1463 L1463 Biomuta DOID:363 / uterine cancer [ icgc ]
S1465 L1465 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1542 L1542 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1550 F1550 Biomuta DOID:4362 / cervical cancer [ icgc ] DOID:1612 / breast cancer [ icgc ]
K1587 R1587 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1718 F1718 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1727 N1727 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1735 F1735 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1760 M1760 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1848 M1848 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1854 M1854 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]