Protein Information

Cytoscape View


UniProt AC / UniProt ID P12755 / SKI_HUMAN
Protein Name Ski oncogene
Gene Name Name: SKI
Organism Homo sapiens (Human)

PRO ID PR:P12755
DAG View
PRO Name ski oncogene (human)
Definition A ski oncogene that is encoded in the genome of human.
Short Label hSKI
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12755 (SKI) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T103 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K318 Acetylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
S326 Phosphorylation O14965 (AURKA) PhosphoSitePlus 26138431
K335 Acetylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
S383 Phosphorylation O14965 (AURKA) PhosphoSitePlus   UniProt 26138431, 23186163
S387 O-Glycosylation GlyGen 28657654, 29351928
S389 O-Glycosylation GlyGen 28657654, 29351928
S394 Phosphorylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
S431 Phosphorylation PhosphoSitePlus
S432 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163
S440 O-Glycosylation GlyGen 28657654, 29351928
T458 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 19875456
S480 Phosphorylation PhosphoSitePlus   UniProt 19690332
S500 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
K584 Ubiquitination PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
K673 Ubiquitination PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S326 F326 Biomuta DOID:1324 / lung cancer [ cosmic ]
S343 F343 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S354 I354 Biomuta DOID:3571 / liver cancer [ icgc ]
S383 F383 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S480 L480 Biomuta DOID:1612 / breast cancer [ icgc ]
S515 C515 Biomuta DOID:1612 / breast cancer [ cosmic ]