iPTMnet Report P12314 FCGR1A

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P12314 / FCGR1_HUMAN
Protein Name	High affinity immunoglobulin gamma Fc receptor I precursor
Gene Name	Name: FCGR1A Synonyms:FCG1,FCGR1,IGFR1;
Organism	Homo sapiens (Human)

PRO ID	PR:P12314 DAG View
PRO Name	high affinity immunoglobulin gamma Fc receptor I (human)
Definition	A high affinity immunoglobulin gamma Fc receptor I that is encoded in the genome of human.
Short Label	hFCGR1A
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P12314 (FCGR1A) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N59	N-Glycosylation		score3	GlyGen UniProt	21965667
	T73	Phosphorylation		score1	PhosphoSitePlus
	S74	Phosphorylation		score1	PhosphoSitePlus
	S76	Phosphorylation		score1	PhosphoSitePlus
	N78	N-Glycosylation		score4	GlyGen UniProt	19159218, 21965667
	Y133	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	18083107
	Y137	Phosphorylation		score1	PhosphoSitePlus
	Y138	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	18083107
	N152	N-Glycosylation		score3	GlyGen UniProt	21965667
	N159	N-Glycosylation		score3	GlyGen UniProt	21965667
	N163	N-Glycosylation		score3	GlyGen UniProt	21965667
	N195	N-Glycosylation		score3	GlyGen UniProt	21965667
	S328	Phosphorylation		score1	PhosphoSitePlus
	S340	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y133	Phosphorylation		score0	HPRD	18083107
	Y138	Phosphorylation		score0	HPRD	18083107

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N159	S159	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]